(Q27622310)

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C G Knight

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R W Farndale

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M J Barnes

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R C Liddington

Cation binding to the integrin CD11b I domain and activation model assessment

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language of work or name

English

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publication date

31 March 2000

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published in

Cell

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volume

101

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page(s)

47-56

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issue

1

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cites work

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7 January 2021

Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution

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The structure of the two amino-terminal domains of human ICAM-1 suggests how it functions as a rhinovirus receptor and as an LFA-1 integrin ligand

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Cloning and expression of the chicken CD18 cDNA.

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

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7 January 2021

Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding activity of the alpha2beta1 integrin

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7 January 2021

Ligand binding results in divalent cation displacement from the alpha 2 beta 1 integrin I domain: evidence from terbium luminescence spectroscopy.

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7 January 2021

Identification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1)

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Crystal structure of the I domain from integrin alpha2beta1

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Crystal structure of the von Willebrand Factor A1 domain and implications for the binding of platelet glycoprotein Ib

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7 January 2021

Integrin alphaIIb beta3 reconstituted into lipid bilayers is nonclustered in its activated state but clusters after fibrinogen binding

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Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

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A binding interface on the I domain of lymphocyte function-associated antigen-1 (LFA-1) required for specific interaction with intercellular adhesion molecule 1 (ICAM-1)

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Folding of the beta-propeller domain of the integrin alphaL subunit is independent of the I domain and dependent on the beta2 subunit

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Folding of the conserved domain but not of flanking regions in the integrin beta2 subunit requires association with the alpha subunit

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7 January 2021

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

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Integrins: versatility, modulation, and signaling in cell adhesion

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Platelets interact with soluble and insoluble collagens through characteristically different reactions.

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Collagen fibril formation

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Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain

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Interaction between collagen and the alpha(2) I-domain of integrin alpha(2)beta(1). Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region

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Affinity modulation of platelet integrin alphaIIbbeta3 by beta3-endonexin, a selective binding partner of the beta3 integrin cytoplasmic tail

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7 January 2021

The collagen-binding A-domains of integrins alpha(1)beta(1) and alpha(2)beta(1) recognize the same specific amino acid sequence, GFOGER, in native (triple-helical) collagens.

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7 January 2021

Alpha L beta 2 integrin/LFA-1 binding to ICAM-1 induced by cytohesin-1, a cytoplasmic regulatory molecule

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Sequence dependent conformational variations of collagen triple-helical structure

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

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7 January 2021

Two conformations of the integrin A-domain (I-domain): a pathway for activation?

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Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures

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The integrin I domain: crystals, metals and related artefacts.

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Cell adhesion in vascular biology. New insights into integrin-ligand interaction

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XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

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Raster3D Version 2.0. A program for photorealistic molecular graphics

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A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding

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7 January 2021

Conformation-dependent platelet adhesion to collagen involving integrin alpha 2 beta 1-mediated and other mechanisms: multiple alpha 2 beta 1-recognition sites in collagen type I.

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7 January 2021

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

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Platelet adhesion to native type I collagen fibrils. Role of GPVI in divalent cation-dependent and -independent adhesion and thromboxane A2 generation

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AMoRe: an automated package for molecular replacement

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7 January 2021

Crystal structure of the alpha1beta1 integrin I-domain: insights into integrin I-domain function

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7 January 2021

Integrin cytoplasmic domains mediate inside-out signal transduction

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7 January 2021

Conformational changes in tertiary structure near the ligand binding site of an integrin I domain.

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The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin

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7 January 2021

Trench-shaped binding sites promote multiple classes of interactions between collagen and the adherence receptors, alpha(1)beta(1) integrin and Staphylococcus aureus cna MSCRAMM

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7 January 2021

Mapping the collagen-binding site in the I domain of the glycoprotein Ia/IIa (integrin alpha(2)beta(1))

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7 January 2021

Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain

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7 January 2021

A discrete site modulates activation of I domains. Application to integrin alphaMbeta2.

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7 January 2021

Identification and reconstruction of the binding site within alphaMbeta2 for a specific and high affinity ligand, NIF

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7 January 2021

Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi

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7 January 2021

Platelet adhesion to collagen. Factors affecting Mg2(+)-dependent and bivalent-cation-independent adhesion

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7 January 2021

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

3794313

3794313

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference