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Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers
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scholarly article
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title
Crystal structure of the worm NitFhit Rosetta Stone protein reveals a Nit tetramer binding two Fhit dimers
(English)
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main subject
crystal structure
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protein structure
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Nit1p YIL164C
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stated in
GOA release 2020-03-11
author
Pawel Bieganowski
object named as
P Bieganowski
series ordinal
5
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Charles Brenner
object named as
C Brenner
series ordinal
8
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Carlo Maria Croce
series ordinal
7
object named as
C M Croce
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author name string
H C Pace
series ordinal
1
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S C Hodawadekar
series ordinal
2
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A Draganescu
series ordinal
3
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J Huang
series ordinal
4
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Y Pekarsky
series ordinal
6
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language of work or name
English
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published in
Current Biology
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volume
10
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issue
15
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page(s)
907-17
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cites work
The FHIT gene 3p14.2 is abnormal in lung cancer.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
Clonal genetic alterations in the lungs of current and former smokers
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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The role of the FHIT/FRA3B locus in cancer
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation
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Crossref
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https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
Expression of abnormal transcripts of the FHIT (fragile histidine triad) gene in ovarian carcinoma.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
FHIT gene alterations in head and neck squamous cell carcinomas
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
Analysis of the FHIT gene and its product in squamous cell carcinomas of the head and neck
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
Muir-Torre-like syndrome in Fhit-deficient mice
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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Crystal structures of HINT demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
The histidine triad superfamily of nucleotide-binding proteins
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
Cloning of the Schizosaccharomyces pombe gene encoding diadenosine 5',5"'-P1,P4-tetraphosphate (Ap4A) asymmetrical hydrolase: sequence similarity with the histidine triad (HIT) protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Replacement of Fhit in cancer cells suppresses tumorigenicity
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Detecting protein function and protein-protein interactions from genome sequences
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein interaction maps for complete genomes based on gene fusion events
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
A combined algorithm for genome-wide prediction of protein function
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stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
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inferred from DOI database lookup
Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Arabidopsis mutants resistant to the auxin effects of indole-3-acetonitrile are defective in the nitrilase encoded by the NIT1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fhit-nucleotide specificity probed with novel fluorescent and fluorogenic substrates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pseudomonas aeruginosa aliphatic amidase is related to the nitrilase/cyanide hydratase enzyme family and Cys166 is predicted to be the active site nucleophile of the catalytic mechanism.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between cellular diadenosine 5',5'''-P1,P4-tetraphosphate level, cell density, cell growth stimulation and toxic stresses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interferons induce accumulation of diadenosine triphosphate (Ap3A) in human cultured cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell cultures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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inferred from DOI database lookup
A multifunctional vector system for heterologous expression of proteins in Escherichia coli. Expression of native and hexahistidyl fusion proteins, rapid purification of the fusion proteins, and removal of fusion peptide by Kex2 protease.
1 reference
stated in
Crossref
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7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of X-ray diffraction data collected in oscillation mode
1 reference
stated in
Crossref
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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Incorporation of prior phase information strengthens maximum-likelihood structure refinement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
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Free R value: cross-validation in crystallography
1 reference
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Crossref
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7 January 2021
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inferred from DOI database lookup
Preliminary X-ray analysis of Escherichia coli GMP synthetase: determination of anomalous scattering factors for a cysteinyl mercury derivative.
1 reference
stated in
Crossref
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https://api.crossref.org/works/10.1016%2FS0960-9822%2800%2900621-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
ALSCRIPT: a tool to format multiple sequence alignments
1 reference
stated in
Crossref
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7 January 2021
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inferred from DOI database lookup
Structural patterns in globular proteins
1 reference
stated in
Crossref
reference URL
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7 January 2021
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Identifiers
DOI
10.1016/S0960-9822(00)00621-7
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4855741
OpenCitations bibliographic resource ID
4855741
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4855741
PubMed ID
10959838
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
4855741
ResearchGate publication ID
12361816
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