(Q27637297)

English

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor

scientific article

NMR Structural Analysis of α-Bungarotoxin and Its Complex with the Principal α-Neurotoxin-binding Sequence on the α7 Subunit of a Neuronal Nicotinic Acetylcholine Receptor

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NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor (English)

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NMR Structural Analysis of α-Bungarotoxin and Its Complex with the Principal α-Neurotoxin-binding Sequence on the α7 Subunit of a Neuronal Nicotinic Acetylcholine Receptor (English)

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

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Leonard Moise

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https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

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Andrea Piserchio

2

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https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

Vladimir J Basus

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Edward Hawrot

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9 April 2017

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5 April 2002

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14 January 2002

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https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

Journal of Biological Chemistry

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https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

277

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https://doi.org/10.1074%2FJBC.M110320200

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14

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9 April 2017

12406-12417

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins.

1 reference

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21 January 2018

The diversity of neuronal nicotinic acetylcholine receptors

1 reference

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21 January 2018

Three-dimensional solution structure of a curaremimetic toxin from Naja nigricollis venom: a proton NMR and molecular modeling study

1 reference

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21 January 2018

Solution structure of LSIII, a long neurotoxin from the venom of Laticauda semifasciata

1 reference

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21 January 2018

Genetic engineering of snake toxins. The functional site of Erabutoxin a, as delineated by site-directed mutagenesis, includes variant residues

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21 January 2018

The crystal structure of alpha-bungarotoxin at 2.5 A resolution: relation to solution structure and binding to acetylcholine receptor

1 reference

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21 January 2018

NMR solution structure of an alpha-bungarotoxin/nicotinic receptor peptide complex

1 reference

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21 January 2018

The solution structure of the complex formed between alpha-bungarotoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica

1 reference

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21 January 2018

Three-dimensional solution structure of the complex of alpha-bungarotoxin with a library-derived peptide

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21 January 2018

A -hairpin structure in a 13-mer peptide that binds -bungarotoxin with high affinity and neutralizes its toxicity

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21 January 2018

NMR mapping and secondary structure determination of the major acetylcholine receptor alpha-subunit determinant interacting with alpha-bungarotoxin

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21 January 2018

The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide

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21 January 2018

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

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21 January 2018

Determination of the primary amino acid sequence specifying the alpha-bungarotoxin binding site on the alpha subunit of the acetylcholine receptor from Torpedo californica

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21 January 2018

Chimeric analysis of a neuronal nicotinic acetylcholine receptor reveals amino acids conferring sensitivity to alpha-bungarotoxin.

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21 January 2018

Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis

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21 January 2018

A neuronal nicotinic acetylcholine receptor subunit (α7) is developmentally regulated and forms a homo-oligomeric channel blocked by α-BTX

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21 January 2018

Characterizing the use of perdeuteration in NMR studies of large proteins: 13C, 15N and 1H assignments of human carbonic anhydrase II.

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Two-dimensional nuclear Overhauser effect: complete relaxation matrix analysis.

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21 January 2018

Overcoming the overlap problem in the assignment of 1H NMR spectra of larger proteins by use of three-dimensional heteronuclear 1H-15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: applicati

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Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

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Distance geometry.

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A structure refinement method based on molecular dynamics in four spatial dimensions.

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Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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MOLMOL: a program for display and analysis of macromolecular structures

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21 January 2018

Automated analysis of interatomic contacts in proteins

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21 January 2018

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

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21 January 2018

Use of nuclear magnetic resonance in probing ligand-macromolecule interactions

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21 January 2018

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

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21 January 2018

The role of cation-pi interactions in biomolecular association. Design of peptides favoring interactions between cationic and aromatic amino acid side chains

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21 January 2018

The functional role of positively charged amino acid side chains in alpha-bungarotoxin revealed by site-directed mutagenesis of a His-tagged recombinant alpha-bungarotoxin.

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21 January 2018

Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity

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21 January 2018

Transcriptional activation domain of the herpesvirus protein VP16 becomes conformationally constrained upon interaction with basal transcription factors.

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21 January 2018

Coupling of local folding to site-specific binding of proteins to DNA

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21 January 2018

Two subsites in the binding domain of the acetylcholine receptor: an aromatic subsite and a proline subsite

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21 January 2018

Orientation of alpha-neurotoxin at the subunit interfaces of the nicotinic acetylcholine receptor

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21 January 2018

Structure, function and properties of antibody binding sites

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21 January 2018

Effects of thio-group modifications on the ion permeability control and ligand binding properties of Torpedo californica acetylcholine receptor

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21 January 2018

Pairwise electrostatic interactions between alpha-neurotoxins and gamma, delta, and epsilon subunits of the nicotinic acetylcholine receptor

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21 January 2018

Identification of equivalent residues in the gamma, delta, and epsilon subunits of the nicotinic receptor that contribute to alpha-bungarotoxin binding

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21 January 2018

Structural and Dynamical Characterization of a Biologically Active Unfolded Fibronectin-Binding Protein fromStaphylococcusaureus†

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21 January 2018

Location of functional regions of acetylcholine receptor α-subunit by site-directed mutagenesis

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21 January 2018

Nicotinic receptors in wonderland

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21 January 2018

Only snake curaremimetic toxins with a fifth disulfide bond have high affinity for the neuronal alpha7 nicotinic receptor

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21 January 2018

The Three-Dimensional NMR Solution Structure of α-Cobratoxin at pH 7.5 and Conformational Differences With the NMR Solution Structure at pH 3.2.

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21 January 2018

Picosecond to hour time scale dynamics of a "three finger" toxin: correlation with its toxic and antigenic properties

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21 January 2018

Structural studies of .alpha.-bungarotoxin. 1. Sequence-specific proton NMR resonance assignments

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21 January 2018

Preliminary Two‐Dimensional [1H]NMR Characterization of the Complex Formed between an 18‐Amino Acid Peptide Fragment of the α‐Subunit of the Nicotinic Acetylcholine Receptor and α‐Bungarotoxina

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21 January 2018

The role of tyrosine at the ligand-binding site of the nicotinic acetylcholine receptor

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Alpha-bungarotoxin binds to human acetylcholine receptor alpha-subunit peptide 185-199 in solution and solid phase but not to peptides 125-147 and 389-409

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Molecular determinants by which a long chain toxin from snake venom interacts with the neuronal alpha 7-nicotinic acetylcholine receptor

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Variability among the sites by which curaremimetic toxins bind to torpedo acetylcholine receptor, as revealed by identification of the functional residues of alpha-cobratoxin

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Stereochemical studies of cyclic peptides. VI. Energy calculations of the cyclic disulphide cysteinyl-cysteine

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Snake venom toxins, unlike smaller antagonists, appear to stabilize a resting state conformation of the nicotinic acetylcholine receptor

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10.1074/JBC.M110320200

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DOI.org query endpoint

https://doi.org/10.1074%2FJBC.M110320200

9 April 2017

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