(Q27637552)

English

The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

The crystal structure of the zymogen catalytic domain of complement protease C1r reveals that a disruptive mechanical stress is required to trigger activation of the C1 complex (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

crystal structure

0 references

1 reference

GOA release 2020-03-11

serine-type endopeptidase activity

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

Christine Gaboriaud

6

0 references

author name string

Monika Budayova-Spano

1

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Monique Lacroix

2

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Nicole M Thielens

3

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Gérard J Arlaud

4

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Juan Carlos Fontecilla-Camps

5

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Christine Gaboriaud

6

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

language of work or name

0 references

publication date

1 February 2002

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

The EMBO Journal

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Europe PubMed Central

PubMed publication ID

5 July 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

3

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

231-239

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

Structure of complement receptor 2 in complex with its C3d ligand

1 reference

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Crystal structure of a complement control protein that regulates both pathways of complement activation and binds heparan sulfate proteoglycans

1 reference

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Structure of a serpin-protease complex shows inhibition by deformation

1 reference

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Crystal structure of the catalytic domain of human complement c1s: a serine protease with a handle

1 reference

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Human plasminogen catalytic domain undergoes an unusual conformational change upon activation

1 reference

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Adhesion mechanism of human beta(2)-glycoprotein I to phospholipids based on its crystal structure.

1 reference

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Structural basis of profactor D activation: from a highly flexible zymogen to a novel self-inhibited serine protease, complement factor D

1 reference

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NMR studies of a viral protein that mimics the regulators of complement activation

1 reference

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1 reference

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Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

2 references

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Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution

1 reference

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20 March 2017

Complete amino acid sequence of the A chain of human complement-classical-pathway enzyme C1r

1 reference

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20 March 2017

Cloning and sequencing of full-length cDNA encoding the precursor of human complement component C1r

1 reference

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Raster3D: photorealistic molecular graphics

2 references

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20 March 2017

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

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The CCP4 suite: programs for protein crystallography

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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Satisfying hydrogen bonding potential in proteins

1 reference

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LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

1 reference

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The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

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20 March 2017

C1q: structure, function, and receptors

1 reference

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Phylogenetic perspectives in innate immunity

1 reference

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20 March 2017

Molecular characterization of a novel serine protease involved in activation of the complement system by mannose-binding protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125823

20 March 2017

Nucleotide sequence of the cDNA coding for human complement C1r

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125823

20 March 2017

NH2-terminal calcium-binding domain of human complement C1s- mediates the interaction of C1r- with C1q

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125823

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Complement system proteins which interact with C3b or C4b A superfamily of structurally related proteins

1 reference

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The N-terminal CUB-epidermal growth factor module pair of human complement protease C1r binds Ca2+ with high affinity and mediates Ca2+-dependent interaction with C1s.

1 reference

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Expression and characterization of a 159 amino acid, N-terminal fragment of human complement component C1s.

1 reference

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1 reference

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Structure and assembly of the catalytic region of human complement protease C1r: a three-dimensional model based on chemical cross-linking and homology modeling.

1 reference

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The instructive role of innate immunity in the acquired immune response

1 reference

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The CUB domain. A widespread module in developmentally regulated proteins

1 reference

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1 reference

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The classical complement pathway: activation and regulation of the first complement component.

1 reference

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Domain structure and associated functions of subcomponents C1r and C1s of the first component of human complement

1 reference

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Active disassembly of the first complement component, C-1, by C-1 inactivator

1 reference

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Interaction properties of human mannan-binding lectin (MBL)-associated serine proteases-1 and -2, MBL-associated protein 19, and MBL.

1 reference

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1 reference

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1 reference

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Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

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12 December 2020

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The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/11823416

12 December 2020

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Conformation and restricted segmental flexibility of C1, the first component of human complement

1 reference

https://pubmed.ncbi.nlm.nih.gov/11823416

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inferred from PubMed ID database lookup

Molecular characterization of the catalytic domains of human complement serine protease C1r

1 reference

https://pubmed.ncbi.nlm.nih.gov/11823416

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Semi-flexible joint in the C1q subunit of the first component of human complement

1 reference

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inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/21.3.231

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 July 2017

ResearchGate publication ID

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