(Q36280463)

English

The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

The co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the Tyr-Pro-Pro-Trp segment and active site residues upon ligand binding (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

M G Malkowski

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

P D Martin

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

J C Guzik

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

B F Edwards

4

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

1 July 1997

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Protein Science

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1438-1448

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Bovine thrombin complexed with an uncleavable analog of residues 7-19 of fibrinogen A alpha: geometry of the catalytic triad and interactions of the P1', P2', and P3' substrate residues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Expression of monocyte chemotactic protein-1 by monocytes and endothelial cells exposed to thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Chemotactic response of monocytes to thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Hydrogen bonding in globular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Bovine chymotrypsinogen A X-ray crystal structure analysis and refinement of a new crystal form at 1.8 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Phosphocholine binding immunoglobulin Fab McPC603. An X-ray diffraction study at 2.7 A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Regulation of thrombin generation and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The roles of protein C and thrombomodulin in the regulation of blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The structure of a complex of recombinant hirudin and human alpha-thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Recombinant human protein C derivatives: altered response to calcium resulting in enhanced activation by thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Crystal structure of the thrombin-hirudin complex: a novel mode of serine protease inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The coagulation cascade: initiation, maintenance, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The interaction of thrombin with fibrinogen. A structural basis for its specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The structure of residues 7-16 of the A alpha-chain of human fibrinogen bound to bovine thrombin at 2.3-A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Partial characterization of vertebrate prothrombin cDNAs: amplification and sequence analysis of the B chain of thrombin from nine different species

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

Characterization of a functional thrombin receptor. Issues and opportunities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The refined 1.9-Å X-ray crystal structure of d-Phe-Pro-Arg chloromethylketone-inhibited human α-thrombin: Structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The Protein Data Bank: a computer-based archival file for macromolecular structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

30 September 2017

The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

29 June 2018

Allosteric changes in thrombin's activity produced by peptides corresponding to segments of natural inhibitors and substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

29 June 2018

Thrombin is a Na(+)-activated enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

29 June 2018

Accurate bond and angle parameters for X-ray protein structure refinement

1 reference

https://api.crossref.org/works/10.1002%2FPRO.5560060708

21 January 2018

Glu192-->Gln substitution in thrombin yields an enzyme that is effectively inhibited by bovine pancreatic trypsin inhibitor and tissue factor pathway inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2143735

22 September 2018

Structure of a bovine thrombin-hirudin51-65 complex determined by a combination of molecular replacement and graphics. Incorporation of known structural information in molecular replacement

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure analysis and refinement of two variants of trigonal trypsinogen: trigonal trypsin and PEG (polyethylene glycol) trypsinogen and their comparison with orthorhombic trypsin and trigonal trypsinogen

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the secondary structure of hirudin and the mechanism of its interaction with thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Meizothrombin, a major product of factor Xa-catalyzed prothrombin activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Na+ binding site of thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of thrombin's Tyr-Pro-Pro-Trp motif in the interaction with fibrinogen, thrombomodulin, protein C, antithrombin III, and the Kunitz inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin cleavage of extracellular matrix proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of hirudin with thrombin: identification of a minimal binding domain of hirudin that inhibits clotting activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anion-binding exosite of human alpha-thrombin and fibrin(ogen) recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trypsin-pancreatic trypsin inhibitor association. Dynamics of the interaction and role of disulfide bridges

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of factor Xa inhibition by tissue factor pathway inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The region of the thrombin receptor resembling hirudin binds to thrombin and alters enzyme specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/9232645

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/PRO.5560060708

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

release_3mbckvtr4naz5ghksfbj7pklsu

1 reference

https://api.fatcat.wiki/v0/release/3mbckvtr4naz5ghksfbj7pklsu

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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