(Q27639018)

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Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks

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Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks (English)

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1

James B Thoden

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Hazel M. Holden

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4

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Hazel M Holden

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Judith L Fridovich-Keil

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3

object named as

Judith L Fridovich-Keil

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Jenny M Henderson

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2

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language of work or name

English

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publication date

26 July 2002

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published in

Journal of Biological Chemistry

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volume

277

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issue

30

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page(s)

27528-34

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Forms and functions of human SDR enzymes

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Short-chain dehydrogenases/reductases (SDR)

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21 January 2018

The fascinating complexities of steroid-binding enzymes

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21 January 2018

Steroid dehydrogenase structures, mechanism of action, and disease

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TIP30, a cofactor for HIV-1 Tat-activated transcription, is homologous to short-chain dehydrogenases/reductases

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A cofactor, TIP30, specifically enhances HIV-1 Tat-activated transcription

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A link between metastasis and resistance to apoptosis of variant small cell lung carcinoma

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The structure of the negative transcriptional regulator NmrA reveals a structural superfamily which includes the short-chain dehydrogenase/reductases

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Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli

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21 January 2018

Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase

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Identification and characterization of a mutation, in the human UDP-galactose-4-epimerase gene, associated with generalized epimerase-deficiency galactosemia

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The enzymic conversion of glucosamine to galactosamine

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21 January 2018

Reversible defects in O-linked glycosylation and LDL receptor expression in a UDP-Gal/UDP-GalNAc 4-epimerase deficient mutant

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Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site

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Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli

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21 January 2018

Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli

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Molecular structure of the NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: implications for the catalytic mechanism

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Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli

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Detection, delineation, measurement and display of cavities in macromolecular structures

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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Identifiers

DOI

10.1074/JBC.M204413200

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PubMed publication ID

12019271

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(Q27639018)

Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks

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