(Q27639097)

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Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization

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Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization (English)

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crystal structure

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Pyrococcus horikoshii

object named as

Pyrococcus horikoshii

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based on heuristic

inferred from title

6

object named as

Kunio Miki

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object named as

Masafumi Yohda

5

1 reference

ORCID Public Data File 2021

author name string

Lijun Liu

1

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Kousuke Iwata

2

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Akiko Kita

3

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Yutaka Kawarabayasi

4

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language of work or name

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publication date

31 May 2002

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Journal of Molecular Biology

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319

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2

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479-89

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Gene for aspartate racemase from the sulfur-dependent hyperthermophilic archaeum, Desulfurococcus strain SY.

1 reference

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The presence of free D-aspartic acid in rodents and man.

1 reference

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Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging.

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Human serine racemase: moleular cloning, genomic organization and functional analysis

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D-aspartate disposition in neuronal and endocrine tissues: ontogeny, biosynthesis and release

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Energetics and mechanism of proline racemase

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Expression of recombinant diaminopimelate epimerase in Escherichia coli. Isolation and inhibition with an irreversible inhibitor

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Mechanism of the reaction catalyzed by glutamate racemase

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Isotope effects and the identification of catalytic residues in the reaction catalyzed by glutamate racemase

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Energetics of proline racemase: transition-state fractionation factors for the two protons involved in the catalytic steps

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Bacterial glutamate racemase has high sequence similarity with myoglobins and forms an equimolar inactive complex with hemin

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Multiple sequence alignment with hierarchical clustering

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Hydrogen bonds and proton transfer in general-catalytic transition-state stabilization in enzyme catalysis.

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Hydrogen bonds involving sulfur atoms in proteins.

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Structural mechanisms for domain movements in proteins

1 reference

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Hard and Soft Acids and Bases

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Catalytic acid/base residues of glutamate racemase

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Crystallization and preliminary X-ray analysis of aspartate racemase from Pyrococcus horikoshii OT3

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10.1016/S0022-2836(02)00296-6

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