(Q27639628)

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Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin

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Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin (English)

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benzylpenicillin

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based on heuristic

inferred from title

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based on heuristic

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author name string

Tatsuro Shimamura

1

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Akiko Ibuka

2

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Shinya Fushinobu

3

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Takayoshi Wakagi

4

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Masaji Ishiguro

5

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Yoshikazu Ishii

6

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Hiroshi Matsuzawa

7

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language of work or name

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publication date

29 November 2002

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Journal of Biological Chemistry

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277

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46601-8

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48

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Catalytic properties of class A beta-lactamases: efficiency and diversity

1 reference

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Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli.

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Crystal structure of the E166A mutant of extended-spectrum beta-lactamase Toho-1 at 1.8 A resolution

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Structure of the extended-spectrum class C beta-lactamase of Enterobacter cloacae GC1, a natural mutant with a tandem tripeptide insertion

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Processing of X-ray diffraction data collected in oscillation mode

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1 reference

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Molecular structure of the acyl-enzyme intermediate in beta-lactam hydrolysis at 1.7 A resolution

1 reference

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A catalytically-impaired class A beta-lactamase: 2 A crystal structure and kinetics of the Bacillus licheniformis E166A mutant

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Crystal structure of Escherichia coli TEM1 beta-lactamase at 1.8 A resolution

1 reference

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Multiple substitutions at position 104 of beta-lactamase TEM-1: assessing the role of this residue in substrate specificity.

1 reference

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TEM beta-lactamase mutants hydrolysing third-generation cephalosporins. A kinetic and molecular modelling analysis.

1 reference

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Effects on substrate profile by mutational substitutions at positions 164 and 179 of the class A TEM(pUC19) beta-lactamase from Escherichia coli.

1 reference

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Role of the omega-loop in the activity, substrate specificity, and structure of class A beta-lactamase

1 reference

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Cephalosporin substrate specificity determinants of TEM-1 beta-lactamase

1 reference

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Cloning of chromosomal beta-lactamase genes from Yersinia enterocolitica

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Mutations in the active site of penicillin-binding protein PBP2x from Streptococcus pneumoniae. Role in the specificity for beta-lactam antibiotics.

1 reference

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An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

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Structure of the SHV-1 beta-lactamase

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Identifiers

10.1074/JBC.M207884200

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release_xithmzfivzbk7kh5rrj43eve7q

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24 November 2022

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