(Q27639919)

2

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David Baker

object named as

David Baker

4

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author name string

Brett S Chevalier

1

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Meggen S Chadsey

3

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Raymond J Monnat

5

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Barry L Stoddard

I-PpoI and I-CreI homing site sequence degeneracy determined by random mutagenesis and sequential in vitro enrichment

6

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language of work or name

English

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publication date

October 2002

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published in

Molecular Cell

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volume

10

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issue

4

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page(s)

895-905

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cites work

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Mechanisms of intron mobility.

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Homing endonucleases: keeping the house in order

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Prokaryotic introns and inteins: a panoply of form and function

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Stimulation of homologous recombination through targeted cleavage by chimeric nucleases

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Enzyme-like proteins by computational design

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Selection of a Remote Cleavage Site by I-TevI, thetdIntron-encoded Endonuclease

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Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility

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The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites

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7 January 2021

The atomic structure of protein-protein recognition sites

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De novo protein design: fully automated sequence selection

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Statistical modeling and analysis of the LAGLIDADG family of site-specific endonucleases and identification of an intein that encodes a site-specific endonuclease of the HNH family

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7 January 2021

Crystal structure of PI-SceI, a homing endonuclease with protein splicing activity

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Bayesian statistical analysis of protein side-chain rotamer preferences

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Directed enzyme evolution

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A novel endonuclease mechanism directly visualized for I-PpoI

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An in vivo selection system for homing endonuclease activity

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Group II introns designed to insert into therapeutically relevant DNA target sites in human cells

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The EcoRI restriction endonuclease with bacteriophage lambda DNA. Kinetic studies

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High-resolution protein design with backbone freedom

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The structure of I-Crel, a group I intron-encoded homing endonuclease

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A revised set of potentials for beta-turn formation in proteins

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Crystal structure of an archaeal intein-encoded homing endonuclease PI-PfuI

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7 January 2021

Evolution and tinkering

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7 January 2021

DNA recognition and cleavage by the LAGLIDADG homing endonuclease I-CreI

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7 January 2021

Native protein sequences are close to optimal for their structures

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7 January 2021

On the possibilities and limitations of rational protein design to expand the specificity of restriction enzymes: a case study employing EcoRV as the target

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Effective energy function for proteins in solution

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Processing of X-ray diffraction data collected in oscillation mode

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Review: protein design--where we were, where we are, where we're going.

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Directed evolution of single proteins, metabolic pathways, and viruses

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7 January 2021

Mutations altering the cleavage specificity of a homing endonuclease

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7 January 2021

Crystal structure of the thermostable archaeal intron-encoded endonuclease I-DmoI

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7 January 2021

A detailed study of the substrate specificity of a chimeric restriction enzyme.

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7 January 2021

Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains

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7 January 2021

Cleavage and recognition pattern of a double-strand-specific endonuclease (I-creI) encoded by the chloroplast 23S rRNA intron of Chlamydomonas reinhardtii

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7 January 2021

WHAT IF: a molecular modeling and drug design program

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7 January 2021

Purification, biochemical characterization and protein-DNA interactions of the I-CreI endonuclease produced in Escherichia coli

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7 January 2021

Protein solubility and folding monitored in vivo by structural complementation of a genetic marker protein

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7 January 2021