(Q27639996)

1

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Stephen Suresh

2

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Goragot Wisedchaisri

3

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Kevin J Kennedy

4

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Wim G J Hol

Molecular mechanisms and therapeutic approaches to the treatment of African trypanosomiasis

6

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publication date

November 2002

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published in

Chemistry and Biology

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volume

9

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issue

11

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page(s)

1189-97

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cites work

1 reference

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7 January 2021

Crystallographic and molecular modeling studies on trypanosomal triosephosphate isomerase: a critical assessment of the predicted and observed structures of the complex with 2-phosphoglycerate

1 reference

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7 January 2021

Structure of the complex between trypanosomal triosephosphate isomerase and N‐hydroxy‐4‐phosphono‐butanamide: Binding at the active site despite an “open” flexible loop conformation

1 reference

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7 January 2021

Structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma brucei determined from Laue data

1 reference

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7 January 2021

Structure-based drug design: progress, results and challenges

1 reference

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7 January 2021

Crystal Structure of Glycosomal Glyceraldehyde-3-phosphate Dehydrogenase from Leishmania mexicana: Implications for Structure-Based Drug Design and a New Position for the Inorganic Phosphate Binding Site

1 reference

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7 January 2021

Synergistic effects of substrate-induced conformational changes in phosphoglycerate kinase activation

1 reference

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7 January 2021

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase

1 reference

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7 January 2021

Adenosine analogues as selective inhibitors of glyceraldehyde-3-phosphate dehydrogenase of Trypanosomatidae via structure-based drug design

1 reference

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7 January 2021

Adenosine analogues as inhibitors of Trypanosoma brucei phosphoglycerate kinase: elucidation of a novel binding mode for a 2-amino-N(6)-substituted adenosine

1 reference

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7 January 2021

Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases

1 reference

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7 January 2021

A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana

1 reference

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7 January 2021

Conformational changes in Leishmania mexicana glyceraldehyde-3-phosphate dehydrogenase induced by designed inhibitors

1 reference

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7 January 2021

Compartmentation of carbohydrate metabolism in trypanosomes

1 reference

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7 January 2021

Metabolic aspects of glycosomes in trypanosomatidae - new data and views

1 reference

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7 January 2021

Glycolysis in bloodstream form Trypanosoma brucei can be understood in terms of the kinetics of the glycolytic enzymes.

1 reference

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7 January 2021

What Controls Glycolysis in Bloodstream FormTrypanosoma brucei?

1 reference

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7 January 2021

Contribution of glucose transport to the control of the glycolytic flux in Trypanosoma brucei

1 reference

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7 January 2021

Metabolic control analysis of glycolysis in trypanosomes as an approach to improve selectivity and effectiveness of drugs.

1 reference

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7 January 2021

Selective tight binding inhibitors of trypanosomal glyceraldehyde-3-phosphate dehydrogenase via structure-based drug design.

1 reference

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7 January 2021

Affinity chromatography using trypanocidal arsenical drugs identifies a specific interaction between glycerol-3-phosphate dehydrogenase from Trypanosoma brucei and Cymelarsan.

1 reference

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7 January 2021

A comparative study of Leishmania mexicana amastigotes and promastigotes, enzyme activities and subcellular locations

1 reference

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7 January 2021

Comparative study of Leishmania mexicana and Trypanosoma brucei NAD-dependent glycerol-3-phosphate dehydrogenase.

1 reference

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7 January 2021

Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments

1 reference

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7 January 2021

Anomalous signal of phosphorus used for phasing DNA oligomer: importance of data redundancy

1 reference

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7 January 2021

Matrix methods for solving protein substructures of chlorine and sulfur from anomalous data

1 reference

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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7 January 2021

Structure of the hydrophobic protein crambin determined directly from the anomalous scattering of sulphur

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

A suite of programs for calculating x‐ray absorption, reflection, and diffraction performance for a variety of materials at arbitrary wavelengths

1 reference

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7 January 2021

Synthesis, cell growth inhibition, and antitumor screening of 2-(p-n-butylanilino)purines and their nucleoside analogues

1 reference

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7 January 2021

Cloning and characterization of the NAD-linked glycerol-3-phosphate dehydrogenases of Trypanosoma brucei brucei and Leishmania mexicana mexicana and expression of the trypanosome enzyme in Escherichia coli.

1 reference

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

On the treatment of negative intensity observations

1 reference

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7 January 2021

Can anomalous signal of sulfur become a tool for solving protein crystal structures?

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

Soft X-rays, high redundancy, and proper scaling: a new procedure for automated protein structure determination via SAS.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

Structure of the Ca2+-regulated photoprotein obelin at 1.7 Å resolution determined directly from its sulfur substructure

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

Raster3D: photorealistic molecular graphics

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900243-0

7 January 2021

10.1016/S1074-5521(02)00243-0

Identifiers

DOI

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Fatcat ID

release_zox2u626qbhzvcjforkuy6og3m

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/zox2u626qbhzvcjforkuy6og3m

24 November 2022