(Q27640455)

1

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Anang A Shelat

2

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David F Savage

3

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Shiou Chuan Tsai

4

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Larry J W Miercke

5

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Joseph D O'Connell

6

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Robert M Stroud

Genetic Contributions to Understanding Polyketide Synthases

8

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publication date

February 2003

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published in

Structure

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volume

11

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issue

2

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page(s)

147-54

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cites work

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7 January 2021

Harnessing the biosynthetic code: combinations, permutations, and mutations

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Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant

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7 January 2021

Malonyl-coenzyme A:acyl carrier protein acyltransferase of Streptomyces glaucescens: a possible link between fatty acid and polyketide biosynthesis.

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7 January 2021

Purification and in vitro reconstitution of the essential protein components of an aromatic polyketide synthase

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7 January 2021

The Escherichia coli malonyl-CoA:acyl carrier protein transacylase at 1.5-A resolution. Crystal structure of a fatty acid synthase component

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7 January 2021

SCOP database in 2002: refinements accommodate structural genomics

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7 January 2021

Structure of the CheY-binding domain of histidine kinase CheA in complex with CheY

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7 January 2021

Novel macrolides through genetic engineering

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7 January 2021

Studies on the mechanism of fatty acid synthesis. XXVI. Purification and properties of malonyl-coenzyme A--acyl carrier protein transacylase of Escherichia coli

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7 January 2021

Crystal structure of the open form of dog gastric lipase in complex with a phosphonate inhibitor

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7 January 2021

Crystal structure of pseudomonas aeruginosa lipase in the open conformation. The prototype for family I.1 of bacterial lipases

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7 January 2021

Alteration of the substrate specificity of a modular polyketide synthase acyltransferase domain through site-specific mutations.

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7 January 2021

Malonyl-CoA:ACP transacylase from Streptomyces coelicolor has two alternative catalytically active nucleophiles

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7 January 2021

Kinetic and mechanistic analysis of the malonyl CoA:ACP transacylase from Streptomyces coelicolor indicates a single catalytically competent serine nucleophile at the active site.

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Divergent sequence motifs correlated with the substrate specificity of (methyl)malonyl-CoA:acyl carrier protein transacylase domains in modular polyketide synthases

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7 January 2021

Characterization of the enzymatic domains in the modular polyketide synthase involved in rifamycin B biosynthesis by Amycolatopsis mediterranei

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7 January 2021

Dissecting the role of acyltransferase domains of modular polyketide synthases in the choice and stereochemical fate of extender units

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7 January 2021

Identification and analysis of the acyl carrier protein (ACP) docking site on beta-ketoacyl-ACP synthase III

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7 January 2021

Crystal structures of substrate binding to Bacillus subtilis holo-(acyl carrier protein) synthase reveal a novel trimeric arrangement of molecules resulting in three active sites

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7 January 2021

Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily

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7 January 2021

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

Raster3D: photorealistic molecular graphics

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7 January 2021

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

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7 January 2021

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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7 January 2021