(Q27641909)

English

Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation

scientific article

In more languages

Statements

scholarly article

0 references

Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation (English)

0 references

author name string

Malcolm Anderson

1

0 references

John F Beattie

2

0 references

Gloria A Breault

3

0 references

Jason Breed

4

0 references

Kate F Byth

5

0 references

Janet D Culshaw

6

0 references

Rebecca P A Ellston

7

0 references

Stephen Green

8

0 references

Claire A Minshull

9

0 references

Richard A Norman

10

0 references

Richard A Pauptit

11

0 references

Judith Stanway

12

0 references

Andrew P Thomas

13

0 references

Philip J Jewsbury

14

0 references

language of work or name

0 references

publication date

15 September 2003

0 references

Bioorganic & Medicinal Chemistry Letters

0 references

13

0 references

18

0 references

3021-6

0 references

Cancer cell cycles

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Anticancer drug targets: cell cycle and checkpoint control.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystallographic approach to identification of cyclin-dependent kinase 4 (CDK4)-specific inhibitors by using CDK4 mimic CDK2 protein

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of selective inhibitors of cyclin dependent kinase 4

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-based generation of a new class of potent Cdk4 inhibitors: new de novo design strategy and library design

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell cycle and biochemical effects of PD 0183812. A potent inhibitor of the cyclin D-dependent kinases CDK4 and CDK6.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective in vivo and in vitro effects of a small molecule inhibitor of cyclin-dependent kinase 4.

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel approach for the development of selective Cdk4 inhibitors: library design based on locations of Cdk4 specific amino acid residues

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of cyclin-dependent kinase 4 (Cdk4) by fascaplysin, a marine natural product

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cinnamaldehydes inhibit cyclin dependent kinase 4/cyclin D1

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

5-Arylamino-2-methyl-4,7-dioxobenzothiazoles as inhibitors of cyclin-dependent kinase 4 and cytotoxic agents

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Structure-based design of a potent purine-based cyclin-dependent kinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: identification and optimisation of substituted 2,4-bis anilino pyrimidines

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitor binding to active and inactive CDK2: the crystal structure of CDK2-cyclin A/indirubin-5-sulphonate

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

A highly specific inhibitor of human p38 MAP kinase binds in the ATP pocket

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase inhibition by staurosporine revealed in details of the molecular interaction with CDK2

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin-Dependent Kinase Inhibition by New C-2 Alkynylated Purine Derivatives and Molecular Structure of a CDK2−Inhibitor Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0960-894X%2803%2900638-3

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0960-894X(03)00638-3

0 references

release_ugdlnikc5ndfpgk6dfc3qxzjvy

0 references

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27641909&oldid=1412904943"