(Q27641940)

1

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Xiaofeng Li

2

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Gang Liu

3

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Cele Abad-Zapatero

4

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Tom Lubben

5

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Tianyuan Zhang

6

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Stephen J Ballaron

7

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Charles W Hutchins

8

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James M Trevillyan

9

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Michael R Jirousek

Bioorganic & Medicinal Chemistry Letters

10

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language of work or name

English

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publication date

6 October 2003

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published in

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volume

13

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issue

19

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page(s)

3129-32

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cites work

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Protein-tyrosine phosphatases: structure, mechanism, and inhibitor discovery

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

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Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

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Protein tyrosine phosphatase 1B inhibitors for diabetes

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Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase-deficient mice

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Coordinated action of protein tyrosine phosphatases in insulin signal transduction

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CD45: new jobs for an old acquaintance

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Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response

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Cell cycle regulation by the Cdc25 phosphatase family

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The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling

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Identification of a second aryl phosphate-binding site in protein-tyrosine phosphatase 1B: a paradigm for inhibitor design

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Acquisition of a specific and potent PTP1B inhibitor from a novel combinatorial library and screening procedure

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Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action

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Examination of novel non-phosphorus-containing phosphotyrosyl mimetics against protein-tyrosine phosphatase-1B and demonstration of differential affinities toward Grb2 SH2 domains

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Utilization of a peptide lead for the discovery of a novel PTP1B-binding motif

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Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B

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Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli

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