(Q34232649)

31 July 2017

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title

CD45: new jobs for an old acquaintance (English)

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31 July 2017

1

Penninger JM

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31 July 2017

Irie-Sasaki J

2

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31 July 2017

Sasaki T

series ordinal

3

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31 July 2017

Oliveira-dos-Santos AJ

series ordinal

4

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31 July 2017

language of work or name

English

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publication date

1 May 2001

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31 July 2017

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31 July 2017

volume

2

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31 July 2017

issue

5

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31 July 2017

page(s)

389-396

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CD45: an emerging role as a protein tyrosine phosphatase required for lymphocyte activation and development

31 July 2017

cites work

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7 January 2021

The leukocyte common antigen family

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7 January 2021

Demonstration that the leukocyte common antigen CD45 is a protein tyrosine phosphatase

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7 January 2021

Normal B lymphocyte development but impaired T cell maturation in CD45-exon6 protein tyrosine phosphatase-deficient mice

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7 January 2021

CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation

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7 January 2021

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

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7 January 2021

Leukocyte common antigen (CD45) is required for immunoglobulin E-mediated degranulation of mast cells

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7 January 2021

Severe combined immunodeficiency with abnormalities in expression of the common leucocyte antigen, CD45

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7 January 2021

Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease

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7 January 2021

A deletion in the gene encoding the CD45 antigen in a patient with SCID.

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7 January 2021

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

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7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

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7 January 2021

Characterization of recombinant CD45 cytoplasmic domain proteins. Evidence for intramolecular and intermolecular interactions

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7 January 2021

Potential positive and negative autoregulation of p60c-src by intermolecular autophosphorylation

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7 January 2021

Structure of the regulatory domains of the Src-family tyrosine kinase Lck

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7 January 2021

Expression of the p56(Lck) Y505F mutation in CD45-deficient mice rescues thymocyte development

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7 January 2021

CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion

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7 January 2021

CD45 modulates phosphorylation of both autophosphorylation and negative regulatory tyrosines of Lyn in B cells

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7 January 2021

Positive and negative regulation of Src-family membrane kinases by CD45.

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7 January 2021

The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity

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7 January 2021

Negative regulation of T-cell receptor signalling by tyrosine protein kinase p50csk

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7 January 2021

Transmembrane phosphoprotein Cbp regulates the activities of Src-family tyrosine kinases

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7 January 2021

Transmembrane Phosphoprotein Cbp Positively Regulates the Activity of the Carboxyl-terminal Src Kinase, Csk

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7 January 2021

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation

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7 January 2021

Tyrosine phosphorylation of CD45 phosphotyrosine phosphatase by p50csk kinase creates a binding site for p56lck tyrosine kinase and activates the phosphatase

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7 January 2021

Demonstration of a direct interaction between p56lck and the cytoplasmic domain of CD45 in vitro

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7 January 2021

Jaks and STATs: biological implications

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7 January 2021

Constitutive activation of JAK1 in Src-transformed cells

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7 January 2021

Abrogation of interleukin-3 dependence of myeloid cells by the v-src oncogene requires SH2 and SH3 domains which specify activation of STATs

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7 January 2021

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

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7 January 2021

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

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7 January 2021

A family of cytokine-inducible inhibitors of signalling

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7 January 2021

A new protein containing an SH2 domain that inhibits JAK kinases

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7 January 2021

The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop

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7 January 2021

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

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7 January 2021

Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction.

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7 January 2021

Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia

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7 January 2021

Proliferation of immature myeloma cells by interleukin-6 is associated with CD45 expression in human multiple myeloma

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7 January 2021

Development of T-leukaemias in CD45 tyrosine phosphatase-deficient mutant lck mice

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7 January 2021

CD45: a leukocyte-specific member of the protein tyrosine phosphatase family

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7 January 2021

CD45 modulates T cell receptor/CD3-induced activation of human thymocytes via regulation of tyrosine phosphorylation

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7 January 2021

Prevention and reversal of renal allograft rejection by antibody against CD45RB

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7 January 2021

Prolongation of xenograft survival using monoclonal antibody CD45RB and cyclophosphamide in rat-to-mouse kidney and heart transplant models

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7 January 2021

Indefinite islet allograft survival in mice after a short course of treatment with anti-CD45 monoclonal antibodies

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7 January 2021

CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway

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7 January 2021

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase

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7 January 2021

Antibody-mediated targeting of CD45 isoforms: a novel immunotherapeutic strategy

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7 January 2021

CTLA-4 up-regulation plays a role in tolerance mediated by CD45.

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7 January 2021

SC35 plays a role in T cell development and alternative splicing of CD45.

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7 January 2021

CD45RA and CD45RBhigh expression induced by thymic selection events

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7 January 2021

Interleukin-4 induces expression of the CD45RA antigen on human thymocyte subpopulations

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7 January 2021

Interconversion of CD45R subsets of CD4 T cells in vivo

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7 January 2021

Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase

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7 January 2021

Regulation of TCR signaling by CD45 lacking transmembrane and extracellular domains

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7 January 2021

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

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7 January 2021

A point mutation in PTPRC is associated with the development of multiple sclerosis

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7 January 2021

Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

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7 January 2021

Role of CD4+CD45RA+ T cells in the development of autoimmune diabetes in the non-obese diabetic (NOD) mouse.

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7 January 2021

Selective enrichment of Th1 CD45RBlow CD4+ T cells in autoimmune infiltrates in experimental allergic encephalomyelitis

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7 January 2021

Deficiency of the expression of CD45RA isoform of CD45 common leukocyte antigen in CD4+ T lymphocytes in children with infantile cholestasis

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7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

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7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

Making the T cell receptor go the distance: a topological view of T cell activation

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7 January 2021

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains

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7 January 2021

Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor

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7 January 2021

A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation

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7 January 2021

Exclusion of CD45 from the T-cell receptor signaling area in antigen-stimulated T lymphocytes

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7 January 2021

Intimate association of Thy-1 and the T-cell antigen receptor with the CD45 tyrosine phosphatase

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7 January 2021

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7 January 2021

Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge

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7 January 2021

Receptor-like protein tyrosine phosphatase alpha homodimerizes on the cell surface

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7 January 2021

Structural basis for inhibition of receptor protein-tyrosine phosphatase-alpha by dimerization

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7 January 2021

An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity

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7 January 2021

Phosphorylation of CD45 by casein kinase 2. Modulation of activity and mutational analysis

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7 January 2021

Protein-tyrosine phosphatase activity of CD45 is activated by sequential phosphorylation by two kinases

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7 January 2021

Differential effect of cholera toxin on CD45RA+ and CD45RO+ T cells: specific inhibition of cytokine production but not proliferation of human naive T cells.

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7 January 2021

Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells

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7 January 2021

The role of CD45 and CD45-associated molecules in T cell activation

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7 January 2021

Identification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45

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7 January 2021

Disruption of lymphocyte function and signaling in CD45-associated protein-null mice

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7 January 2021

Biochemical analysis of the CD45-p56(lck) complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein

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7 January 2021

CD45-associated protein is not essential for the regulation of antigen receptor-mediated signal transduction

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7 January 2021

The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and alpha 2-6 sialyltransferase, CD75, on B cells

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7 January 2021

Characterization of the interaction between galectin-1 and lymphocyte glycoproteins CD45 and Thy-1

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7 January 2021

Apoptosis of T cells mediated by galectin-1.

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7 January 2021

Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation

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7 January 2021

Antiproliferative action of interferon-α requires components of T-cell-receptor signalling

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7 January 2021

Identifiers

DOI

10.1038/87687

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1 reference