(Q27641963)

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The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold

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The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold (English)

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crystal structure

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Mycobacterium tuberculosis

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author name string

Jason T Maynes

1

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Craig Garen

2

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Maia M Cherney

3

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Gerald Newton

4

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Dorit Arad

5

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Yossef Av-Gay

6

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Robert C Fahey

7

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Michael N G James

8

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language of work or name

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publication date

21 November 2003

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Journal of Biological Chemistry

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278

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47

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47166-70

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Consensus statement. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. WHO Global Surveillance and Monitoring Project

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Phenothiazines: potential alternatives for the management of antibiotic resistant infections of tuberculosis and malaria in developing countries

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Distribution of thiols in microorganisms: mycothiol is a major thiol in most actinomycetes

1 reference

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Mycothiol, 1-O-(2'-[N-acetyl-L-cysteinyl]amido-2'-deoxy-alpha-D-glucopyranosyl)-D- myo-inositol, is the factor of NAD/factor-dependent formaldehyde dehydrogenase

1 reference

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Mycothiol-dependent formaldehyde dehydrogenase, a prokaryotic medium-chain dehydrogenase/reductase, phylogenetically links different eukaroytic alcohol dehydrogenases--primary structure, conformational modelling and functional correlations

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Characterization of Mycobacterium smegmatis mutants defective in 1-d-myo-inosityl-2-amino-2-deoxy-alpha-d-glucopyranoside and mycothiol biosynthesis

1 reference

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A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase

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Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics.

1 reference

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The glycosyltransferase gene encoding the enzyme catalyzing the first step of mycothiol biosynthesis (mshA)

1 reference

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N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis

1 reference

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ATP-dependent L-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase, mycothiol biosynthesis enzyme MshC, is related to class I cysteinyl-tRNA synthetases

1 reference

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Identification of the mycothiol synthase gene (mshD) encoding the acetyltransferase producing mycothiol in actinomycetes

1 reference

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Association of mycothiol with protection of Mycobacterium tuberculosis from toxic oxidants and antibiotics

1 reference

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Mycothiol biochemistry

1 reference

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The CCP4 suite: programs for protein crystallography

1 reference

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Map-likelihood phasing

1 reference

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Automated protein model building combined with iterative structure refinement

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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XtalView/Xfit--A versatile program for manipulating atomic coordinates and electron density

1 reference

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A comparison of the structures of apo dogfish M4 lactate dehydrogenase and its ternary complexes

1 reference

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Protein structure comparison by alignment of distance matrices

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Probing the atomic interactions between proteins and carbohydrates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308914200

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Refined crystal structure of carboxypeptidase A at 1.54 A resolution

1 reference

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Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.

1 reference

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The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductase

1 reference

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SWISS-MODEL: An automated protein homology-modeling server

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308914200

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Automated structure solution, density modification and model building

1 reference

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Identifiers

10.1074/JBC.M308914200

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release_gj2tdg43bzhr7li6iiu4pew7jy

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