(Q40699796)

English

Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite.

scientific article published on 2 October 2002

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Cloning of Trypanosoma brucei and Leishmania major genes encoding the GlcNAc-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol biosynthesis that is essential to the African sleeping sickness parasite (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Trypanosoma brucei

0 references

N-acetyl-D-acetylglucosaminylphosphatidylinositol deacetylase

1 reference

5 February 2019

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

1 reference

6 February 2019

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

0 references

N-acetylglucosaminyl-phosphatidylinositol deacetylase, putative

0 references

N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative

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N-Acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase, putative

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N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

0 references

N-acetyl-D-glucosaminylphosphatidylinositol de-N-acetylase

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African trypanosomiasis

1 reference

based on heuristic

inferred from title

Leishmania major

object named as

Leishmania major

1 reference

based on heuristic

inferred from title

Michael J. Ferguson

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

author name string

Tunhan Chang

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Kenneth G Milne

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Maria Lucia Sampaio Güther

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Terry K Smith

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

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publication date

2 October 2002

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30 August 2019

number of pages

7

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inferred from page(s)

Journal of Biological Chemistry

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

277

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

51

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30 August 2019

50176-50182

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Secretory pathway of trypanosomatid parasites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Glycoconjugate structures of parasitic protozoa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Antigenic variation in trypanosomes: secrets surface slowly

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Proteophosphoglycans of Leishmania

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Glycosylphosphatidylinositol biosynthesis validated as a drug target for African sleeping sickness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Glycosylation defects and virulence phenotypes of Leishmania mexicana phosphomannomutase and dolicholphosphate-mannose synthase gene deletion mutants

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Lipophosphoglycan is a virulence factor distinct from related glycoconjugates in the protozoan parasite Leishmania major.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Is lipophosphoglycan a virulence factor? A surprising diversity between Leishmania species

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Early steps in glycosylphosphatidylinositol biosynthesis in Leishmania major.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Intracellular trafficking of glycosylphosphatidylinositol (GPI)-anchored proteins and free GPIs in Leishmania mexicana

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

YLL031c belongs to a novel family of membrane proteins involved in the transfer of ethanolaminephosphate onto the core structure of glycosylphosphatidylinositol anchors in yeast

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Mammalian glycophosphatidylinositol anchor transfer to proteins and posttransfer deacylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Expression cloning of PIG-L, a candidate N-acetylglucosaminyl-phosphatidylinositol deacetylase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Substrate specificity of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol membrane anchor biosynthesis in African trypanosomes and human cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Differences between the trypanosomal and human GlcNAc-PI de-N-acetylases of glycosylphosphatidylinositol membrane anchor biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Specificity of GlcNAc-PI de-N-acetylase of GPI biosynthesis and synthesis of parasite-specific suicide substrate inhibitors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

A tightly regulated inducible expression system for conditional gene knock-outs and dominant-negative genetics in Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Acyl-CoA binding protein is essential in bloodstream form Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Galactose metabolism is essential for the African sleeping sickness parasite Trypanosoma brucei

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Substrate specificity of the dolichol phosphate mannose: glucosaminyl phosphatidylinositol alpha1-4-mannosyltransferase of the glycosylphosphatidylinositol biosynthetic pathway of African trypanosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Active site determination of Gpi8p, a caspase-related enzyme required for glycosylphosphatidylinositol anchor addition to proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Parasite glycoconjugates. Part 1. The synthesis of some early and related intermediates in the biosynthetic pathway of glycosyl-phosphatidylinositol membrane anchors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

A novel pathway for glycan assembly: biosynthesis of the glycosyl-phosphatidylinositol anchor of the trypanosome variant surface glycoprotein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Fatty acid remodeling: A novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Glycosyl Phosphatidylinositol Myristoylation in African Trypanosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Identification of complete precursors for the glycosylphosphatidylinositol protein anchors of Trypanosoma cruzi

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Glucosylation of Glycosylphosphatidylinositol Membrane Anchors: Identification of Uridine Diphosphate−Glucose as the Direct Donor for Side Chain Modification inToxoplasma gondiiUsing Carbohydrate Analogues†

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Delineation of three pathways of glycosylphosphatidylinositol biosynthesis in Leishmania mexicana. Precursors from different pathways are assembled on distinct pools of phosphatidylinositol and undergo fatty acid remodeling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208374200

21 January 2018

Identifiers

10.1074/JBC.M208374200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12364327%20AND%20SRC:MED&resulttype=core&format=json

30 August 2019

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