(Q27642925)

1

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David J Hosfield

2

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Seungil Han

3

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Junzhuan Qiu

4

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Biana Yelent

5

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Binghui Shen

6

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John A Tainer

Modeling of Flap Endonuclease Interactions with DNA Substrate

7

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language of work or name

English

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publication date

9 January 2004

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published in

Cell

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volume

116

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issue

1

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page(s)

39-50

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cites work

1 reference

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7 January 2021

A mutational analysis of the yeast proliferating cell nuclear antigen indicates distinct roles in DNA replication and DNA repair

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7 January 2021

Enzymes and reactions at the eukaryotic DNA replication fork

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7 January 2021

Effect of flap modifications on human FEN1 cleavage.

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7 January 2021

Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the -clamp

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7 January 2021

A helical arch allowing single-stranded DNA to thread through T5 5'-exonuclease

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7 January 2021

Fluorescence resonance energy transfer and nucleic acids

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7 January 2021

Observing the helical geometry of double-stranded DNA in solution by fluorescence resonance energy transfer

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7 January 2021

Interactions of mutant and wild-type flap endonucleases with oligonucleotide substrates suggest an alternative model of DNA binding

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7 January 2021

Mutations in yeast proliferating cell nuclear antigen define distinct sites for interaction with DNA polymerase delta and DNA polymerase epsilon

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7 January 2021

Stimulation of eukaryotic flap endonuclease-1 activities by proliferating cell nuclear antigen (PCNA) is independent of its in vitro interaction via a consensus PCNA binding region

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7 January 2021

The acetylatable lysines of human Fen1 are important for endo- and exonuclease activities

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7 January 2021

Two modes of FEN1 binding to PCNA regulated by DNA.

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7 January 2021

Structure of the C-terminal region of p21(WAF1/CIP1) complexed with human PCNA

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7 January 2021

Functional domains within FEN-1 and RAD2 define a family of structure-specific endonucleases: implications for nucleotide excision repair

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7 January 2021

Flap endonuclease 1: a novel tumour suppresser protein

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7 January 2021

Newly discovered archaebacterial flap endonucleases show a structure-specific mechanism for DNA substrate binding and catalysis resembling human flap endonuclease-1.

1 reference

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7 January 2021

Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity

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7 January 2021

The crystal structure of flap endonuclease-1 from Methanococcus jannaschii

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7 January 2021

Evidence for involvement of yeast proliferating cell nuclear antigen in DNA mismatch repair

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7 January 2021

Regulation of DNA replication and repair proteins through interaction with the front side of proliferating cell nuclear antigen

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7 January 2021

A comparison of eubacterial and archaeal structure-specific 5'-exonucleases

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7 January 2021

Cleavage specificity of Saccharomyces cerevisiae flap endonuclease 1 suggests a double-flap structure as the cellular substrate

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7 January 2021

Direct interaction between mammalian DNA polymerase beta and proliferating cell nuclear antigen.

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7 January 2021

Crystal structure of Thermus aquaticus DNA polymerase

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7 January 2021

Human flap endonuclease-1: conformational change upon binding to the flap DNA substrate and location of the Mg2+ binding site

1 reference

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7 January 2021

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

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7 January 2021

Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA

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7 January 2021

Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression

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https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Crystal structure of NAD+-dependent DNA ligase: modular architecture and functional implications

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7 January 2021

Lagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

The FEN-1 family of structure-specific nucleases in eukaryotic DNA replication, recombination and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Okazaki fragment processing: modulation of the strand displacement activity of DNA polymerase delta by the concerted action of replication protein A, proliferating cell nuclear antigen, and flap endonuclease-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Molecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshii

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Crystal structure of an archaeal DNA sliding clamp: proliferating cell nuclear antigen from Pyrococcus furiosus

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus

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7 January 2021

Molecular mechanism of PCNA-dependent base excision repair

1 reference

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7 January 2021

Structure of bacteriophage T4 RNase H, a 5' to 3' RNA-DNA and DNA-DNA exonuclease with sequence similarity to the RAD2 family of eukaryotic proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Arginine residues 47 and 70 of human flap endonuclease-1 are involved in DNA substrate interactions and cleavage site determination

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

The kinetics of oligonucleotide replacements

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https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Building a replisome from interacting pieces: sliding clamp complexed to a peptide from DNA polymerase and a polymerase editing complex

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Flap endonuclease homologs in archaebacteria exist as independent proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Mechanism whereby proliferating cell nuclear antigen stimulates flap endonuclease 1

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

PCNA binding through a conserved motif

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Identification of rad27 mutations that confer differential defects in mutation avoidance, repeat tract instability, and flap cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021

Clamp loading, unloading and intrinsic stability of the PCNA, beta and gp45 sliding clamps of human, E. coli and T4 replicases

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2803%2901036-5

7 January 2021