(Q27642935)

3

0 references

R. John Collier

object named as

R John Collier

6

0 references

Lewis C. Cantley

object named as

Lewis C Cantley

8

0 references

Stephen H. Leppla

5

object named as

Stephen H Leppla

0 references

author name string

Benjamin E Turk

1

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Thiang Yian Wong

2

0 references

Emily T Jarrell

4

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Robert C Liddington

Nature Structural & Molecular Biology

7

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language of work or name

1 reference

January 2004

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published in

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volume

11

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page(s)

60-6

0 references

issue

1

0 references

1 reference

21 January 2018

1 reference

Bacillus anthracis lethal toxin induces TNF-alpha-independent hypoxia-mediated toxicity in mice

21 January 2018

1 reference

Designing a polyvalent inhibitor of anthrax toxin

21 January 2018

1 reference

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

21 January 2018

1 reference

Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

21 January 2018

1 reference

Anthrax lethal factor cleaves MKK3 in macrophages and inhibits the LPS/IFNgamma-induced release of NO and TNFalpha

21 January 2018

1 reference

Susceptibility of mitogen-activated protein kinase kinase family members to proteolysis by anthrax lethal factor

21 January 2018

1 reference

Regulation of MAP kinases by docking domains

21 January 2018

1 reference

Impairment of dendritic cells and adaptive immunity by anthrax lethal toxin

21 January 2018

1 reference

On the role of macrophages in anthrax

21 January 2018

1 reference

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

21 January 2018

1 reference

Anthrax lethal factor proteolysis and inactivation of MAPK kinase.

21 January 2018

1 reference

A peptide-based fluorescence resonance energy transfer assay for Bacillus anthracis lethal factor protease

21 January 2018

1 reference

Screening inhibitors of anthrax lethal factor

21 January 2018

1 reference

SH2 domains recognize specific phosphopeptide sequences

21 January 2018

1 reference

Determination of protease cleavage site motifs using mixture-based oriented peptide libraries

21 January 2018

1 reference

A conserved docking motif in MAP kinases common to substrates, activators and regulators

21 January 2018

1 reference

Molecular determinants that mediate selective activation of p38 MAP kinase isoforms

21 January 2018

1 reference

Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking

21 January 2018

1 reference

Metal-coordinating substrate analogs as inhibitors of metalloenzymes

21 January 2018

1 reference

Purification of human collagenases with a hydroxamic acid affinity column

21 January 2018

1 reference

Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids

21 January 2018

1 reference

Matrix metalloproteinase inhibitors: a structure-activity study

21 January 2018

1 reference

Crystal structure of the anthrax lethal factor

21 January 2018

1 reference

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis

21 January 2018

1 reference

X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design

21 January 2018

1 reference

Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases

21 January 2018

1 reference

Crystal structure of the stromelysin catalytic domain at 2.0 A resolution: inhibitor-induced conformational changes

21 January 2018

1 reference

Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor

21 January 2018

1 reference

Identification of small molecule inhibitors of anthrax lethal factor

21 January 2018

1 reference

Ltx1, a mouse locus that influences the susceptibility of macrophages to cytolysis caused by intoxication with Bacillus anthracis lethal factor, maps to chromosome 11.

21 January 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

Structure of trypanothione reductase from Crithidia fasciculata at 2.6 A resolution; enzyme-NADP interactions at 2.8 A resolution.

21 January 2018

1 reference

Dominant-Negative Mutants of a Toxin Subunit: An Approach to Therapy of Anthrax

21 January 2018

1 reference

Inhibition of matrix metalloproteinases by hydroxamates containing heteroatom-based modifications of the P1' group

21 January 2018

1 reference

X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily

31 March 2020

1 reference

Lethal factor active-site mutations affect catalytic activity in vitro.

31 March 2020

1 reference