(Q27643106)

1

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Bjarke E Hansen

Bjarke E Hansen

2

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Lars Fugger

10

Lars Fugger

0 references

Jack L. Strominger

8

Jack L Strominger

0 references

Yvonne Jones

9

E Yvonne Jones

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author name string

Jessica R Wyer

3

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Robert E Esnouf

5

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Arne Svejgaard

6

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John I Bell

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

17 February 2004

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published in

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volume

101

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issue

7

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page(s)

1999-2004

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cites work

Structure of a human insulin peptide-HLA-DQ8 complex and susceptibility to type 1 diabetes

1 reference

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Structural basis of peptide binding and presentation by the type I diabetes-associated MHC class II molecule of NOD mice

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Crystal structure of cat muscle pyruvate kinase at a resolution of 2.6 A

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Rapid automated molecular replacement by evolutionary search

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

2 references

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20 March 2017

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Errors in protein structures

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

20 March 2017

https://api.crossref.org/works/10.1073/PNAS.0308458100

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Processing of X-ray diffraction data collected in oscillation mode

20 March 2017

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

22 April 2017

1 reference

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Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

22 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

The role of hypocretins (orexins) in sleep regulation and narcolepsy.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

CSF hypocretin/orexin levels in narcolepsy and other neurological conditions.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Genetic protection from the inflammatory disease type 1 diabetes in humans and animal models

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Narcolepsy: clinical features, new pathophysiologic insights, and future perspectives

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Regulatory T cells: key controllers of immunologic self-tolerance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Functional characterization of HLA-DRA1*0101/DRB1*0401 molecules expressed in Drosophila melanogaster cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

A mechanism for the major histocompatibility complex-linked resistance to autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Autoimmune hypothesis in narcolepsy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Analysis of HLA-DQ genotypes and susceptibility in insulin-dependent diabetes mellitus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Production of soluble MHC class II proteins with covalently bound single peptides

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

DQ (rather than DR) gene marks susceptibility to narcolepsy

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

HLA DR15 (DR2) and DQB1*0602 typing studies in 188 narcoleptic patients with cataplexy

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308458100

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308458100

Expression of recombinant HLA-DR2 molecules. Replacement of the hydrophobic transmembrane region by a leucine zipper dimerization motif allows the assembly and secretion of soluble DR alpha beta heterodimers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0308458100

A peptide binding motif for HLA-DQA1*0102/DQB1*0602, the class II MHC molecule associated with dominant protection in insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=357041

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

27 November 2018

1 reference

12 December 2020

1 reference

12 December 2020

Narcolepsy and immunity

1 reference

12 December 2020

Insulin-dependent diabetes mellitus

1 reference

12 December 2020

Limited loss of tolerance to islet autoantigens in ICA+ first degree relatives of patients with type I diabetes expressing the HLA dqb1*0602 allele

1 reference

12 December 2020

Antiislet autoantibodies usually develop sequentially rather than simultaneously

1 reference

12 December 2020