(Q27644620)

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The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity

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scholarly article

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The crystal structure of the ivy Delta4-16:0-ACP desaturase reveals structural details of the oxidized active site and potential determinants of regioselectivity (English)

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crystal structure

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4

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object named as

John Shanklin

5

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author name string

Jodie E Guy

1

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Edward Whittle

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Desigan Kumaran

3

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language of work or name

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publication date

6 July 2007

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Journal of Biological Chemistry

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282

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27

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19863-71

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Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs

1 reference

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Primary structures of the precursor and mature forms of stearoyl-acyl carrier protein desaturase from safflower embryos and requirement of ferredoxin for enzyme activity

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21 January 2018

Fatty acid desaturases: selecting the dehydrogenation channel

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DESATURATION AND RELATED MODIFICATIONS OF FATTY ACIDS1

1 reference

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X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv

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Expression of a delta 9 14:0-acyl carrier protein fatty acid desaturase gene is necessary for the production of omega 5 anacardic acids found in pest-resistant geranium (Pelargonium xhortorum).

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Characterization of a structurally and functionally diverged acyl-acyl carrier protein desaturase from milkweed seed

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A determinant of substrate specificity predicted from the acyl-acyl carrier protein desaturase of developing cat's claw seed

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cDNAs for isoforms of the delta 9-stearoyl-acyl carrier protein desaturase from Thunbergia alata endosperm

1 reference

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21 January 2018

Expression of a coriander desaturase results in petroselinic acid production in transgenic tobacco

1 reference

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A multifunctional acyl-acyl carrier protein desaturase from Hedera helix L. (English ivy) can synthesize 16- and 18-carbon monoene and diene products

1 reference

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21 January 2018

Azide and acetate complexes plus two iron-depleted crystal structures of the di-iron enzyme delta9 stearoyl-acyl carrier protein desaturase. Implications for oxygen activation and catalytic intermediates

1 reference

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Redesign of soluble fatty acid desaturases from plants for altered substrate specificity and double bond position

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Engineering delta 9-16:0-acyl carrier protein (ACP) desaturase specificity based on combinatorial saturation mutagenesis and logical redesign of the castor delta 9-18:0-ACP desaturase

1 reference

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21 January 2018

Stereochemistry of Delta4 dehydrogenation catalyzed by an ivy (Hedera helix) Delta9 desaturase homolog.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702520200

21 January 2018

Site-directed mutagenesis by overlap extension using the polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702520200

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Processing of X-ray diffraction data collected in oscillation mode

1 reference

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MOLREP: an Automated Program for Molecular Replacement

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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Coot: model-building tools for molecular graphics

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702520200

21 January 2018

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702520200

21 January 2018

Solvent content of protein crystals

1 reference

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21 January 2018

Resonance Raman evidence for an Fe-O-Fe center in stearoyl-ACP desaturase. Primary sequence identity with other diiron-oxo proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M702520200

21 January 2018

Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane

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Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states.

1 reference

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21 January 2018

A single mutation in the castor Delta9-18:0-desaturase changes reaction partitioning from desaturation to oxidase chemistry

1 reference

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21 January 2018

Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site

1 reference

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21 January 2018

Effect of substrate on the diiron(III) site in stearoyl acyl carrier protein delta 9-desaturase as disclosed by cryoreduction electron paramagnetic resonance/electron nuclear double resonance spectroscopy.

1 reference

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Substrate-dependent mutant complementation to select fatty acid desaturase variants for metabolic engineering of plant seed oils

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M702520200

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release_c73gndh3kzdfjlmpvjnixbbcsq

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