(Q27644674)

English

Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway

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scholarly article

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Structure of a SUMO-binding-motif Mimic Bound to Smt3p–Ubc9p: Conservation of a Non-covalent Ubiquitin-like Protein–E2 Complex as a Platform for Selective Interactions within a SUMO Pathway (English)

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protein structure

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author name string

David M Duda

1

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Robert C A M van Waardenburg

2

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Laura A Borg

3

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Sierra McGarity

4

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Amanda Nourse

5

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M Brett Waddell

6

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Mary-Ann Bjornsti

7

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Brenda A Schulman

8

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language of work or name

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publication date

8 June 2007

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Journal of Molecular Biology

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369

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3

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619-30

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1 reference

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Crystal structure of the SENP1 mutant C603S-SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease

1 reference

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Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex

1 reference

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Structural basis for recruitment of Ubc12 by an E2 binding domain in NEDD8's E1

1 reference

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20 March 2017

Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1

1 reference

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Insights into the ubiquitin transfer cascade from the structure of the activating enzyme for NEDD8

1 reference

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20 March 2017

Solution structure of a yeast ubiquitin-like protein Smt3: The role of structurally less defined sequences in protein-protein recognitions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover

1 reference

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20 March 2017

Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

1 reference

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2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

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Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast

1 reference

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20 March 2017

Structure determination of the small ubiquitin-related modifier SUMO-1

1 reference

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20 March 2017

SUMO-1 modification and its role in targeting the Ran GTPase-activating protein, RanGAP1, to the nuclear pore complex

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

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20 March 2017

Yeast Ull1/Siz1 is a novel SUMO1/Smt3 ligase for septin components and functions as an adaptor between conjugating enzyme and substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

The ubiquitin-like proteins SMT3 and SUMO-1 are conjugated by the UBC9 E2 enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

Ubc9p is the conjugating enzyme for the ubiquitin-like protein Smt3p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

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The nucleoporin RanBP2 has SUMO1 E3 ligase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

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The polycomb protein Pc2 is a SUMO E3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

Role of an N-terminal site of Ubc9 in SUMO-1, -2, and -3 binding and conjugation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

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1 reference

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20 March 2017

Involvement of PIAS1 in the sumoylation of tumor suppressor p53

1 reference

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20 March 2017

An E3-like factor that promotes SUMO conjugation to the yeast septins

1 reference

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20 March 2017

Modification of proteins by ubiquitin and ubiquitin-like proteins

1 reference

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Something about SUMO inhibits transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

20 March 2017

SUMO: a history of modification

2 references

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20 March 2017

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Solution structure of human SUMO-3 C47S and its binding surface for Ubc9

1 reference

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20 March 2017

Crystal structure of thymine DNA glycosylase conjugated to SUMO-1

1 reference

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20 March 2017

Protein modification by SUMO

1 reference

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7 April 2017

Mms2-Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation

1 reference

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7 April 2017

Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

7 April 2017

Ubiquitin: structures, functions, mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

7 April 2017

Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates

1 reference

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Distinct functional domains of Ubc9 dictate cell survival and resistance to genotoxic stress

1 reference

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29 September 2017

Specification of SUMO1- and SUMO2-interacting motifs

1 reference

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29 September 2017

Structural basis for SUMO-E2 interaction revealed by a complex model using docking approach in combination with NMR data

1 reference

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29 September 2017

SUMO protein modification.

1 reference

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29 September 2017

Identification of a SUMO-binding motif that recognizes SUMO-modified proteins

1 reference

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29 September 2017

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1 reference

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29 September 2017

Identification of a multifunctional binding site on Ubc9p required for Smt3p conjugation

1 reference

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29 September 2017

RanBP2 associates with Ubc9p and a modified form of RanGAP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1936411

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Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.

1 reference

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2 June 2018

The binding interface between an E2 (UBC9) and a ubiquitin homologue (UBL1).

1 reference

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2 June 2018

Small ubiquitin-like modifier (SUMO) recognition of a SUMO binding motif: a reversal of the bound orientation

1 reference

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Defects in SUMO (small ubiquitin-related modifier) conjugation and deconjugation alter cell sensitivity to DNA topoisomerase I-induced DNA damage.

1 reference

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The SUMO isopeptidase Ulp2 prevents accumulation of SUMO chains in yeast

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Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination

1 reference

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A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/17475278

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.JMB.2007.04.007

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release_w2lx5l2norh7lpeesjumkdppeq

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