(Q27645935)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

0 references

1

1 reference

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31 December 2019

Brian J. Smith

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

Walter D Fairlie

7

1 reference

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31 December 2019

author name string

P E Czabotar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

K Deshayes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

K Zobel

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

P M Colman

6

1 reference

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31 December 2019

publication date

15 June 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

31 December 2019

published in

1 reference

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31 December 2019

volume

14

1 reference

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31 December 2019

issue

9

1 reference

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31 December 2019

page(s)

1711-1713

1 reference

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Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

31 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

Structural insights into the degradation of Mcl-1 induced by BH3 domains

21 April 2017

1 reference

https://api.crossref.org/works/10.1038/SJ.CDD.4402178

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

The Bcl-2 family: roles in cell survival and oncogenesis.

21 April 2017

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

21 January 2018

At the gates of death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

The structure of a Bcl-xL/Bim fragment complex: implications for Bim function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

Rationale for Bcl-xL/Bad peptide complex formation from structure, mutagenesis, and biophysical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

Promoting apoptosis as a strategy for cancer drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

BH3-only proteins: orchestrating cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

7 January 2021

Comparison of chemical inhibitors of antiapoptotic Bcl-2-family proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

7 January 2021

A novel Bcl-2/Bcl-X(L)/Bcl-w inhibitor ABT-737 as therapy in multiple myeloma.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

7 January 2021

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402178

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402178

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17572662%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 December 2019

1017257972

0 references

1 reference