(Q27646517)

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Electrostatic Interactions of Hsp-organizing Protein Tetratricopeptide Domains with Hsp70 and Hsp90: COMPUTATIONAL ANALYSIS AND PROTEIN ENGINEERING

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Europe PubMed Central

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2 February 2020

Electrostatic interactions of Hsp-organizing protein tetratricopeptide domains with Hsp70 and Hsp90: computational analysis and protein engineering (English)

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2 February 2020

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computational biology

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inferred from title

1

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2 February 2020

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2 February 2020

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Lynne Regan

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2 February 2020

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Jonathan N Sachs

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2 February 2020

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7 July 2009

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2 February 2020

Journal of Biological Chemistry

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2 February 2020

284

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2 February 2020

37

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2 February 2020

25364-25374

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2 February 2020

Ligand binding by TPR domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

20 March 2017

Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine

1 reference

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20 March 2017

Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90

1 reference

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20 March 2017

All-atom empirical potential for molecular modeling and dynamics studies of proteins

1 reference

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Coot: model-building tools for molecular graphics

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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Automated protein model building combined with iterative structure refinement

1 reference

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20 March 2017

Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery

1 reference

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20 March 2017

The carboxy-terminal domain of Hsc70 provides binding sites for a distinct set of chaperone cofactors

1 reference

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20 March 2017

Structure and mechanism of the Hsp90 molecular chaperone machinery

1 reference

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7 April 2017

Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery

1 reference

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The penultimate rotamer library

1 reference

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7 April 2017

A novel class of small molecule inhibitors of Hsp90.

1 reference

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29 September 2017

The Hsp90 chaperone machinery

1 reference

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29 September 2017

The glucocorticoid responses are shaped by molecular chaperones

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29 September 2017

Role of molecular chaperones in steroid receptor action

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29 September 2017

Protein design to understand peptide ligand recognition by tetratricopeptide repeat proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Tetratricopeptide repeat motif-mediated Hsc70-mSTI1 interaction. Molecular characterization of the critical contacts for successful binding and specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Hsp90 inhibitors as novel cancer chemotherapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Ligand discrimination by TPR domains. Relevance and selectivity of EEVD-recognition in Hsp70 x Hop x Hsp90 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Hsp90: chaperoning signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Macromolecular electrostatics: continuum models and their growing pains

1 reference

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29 September 2017

Tanford-Kirkwood electrostatics for protein modeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

Electrostatic interactions in the GCN4 leucine zipper: substantial contributions arise from intramolecular interactions enhanced on binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

The effect of protein relaxation on charge-charge interactions and dielectric constants of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2757238

29 September 2017

On the role of electrostatic interactions in the design of protein-protein interfaces

1 reference

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2 June 2018

Predicting the rate enhancement of protein complex formation from the electrostatic energy of interaction.

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Stress-inducible, murine protein mSTI1. Characterization of binding domains for heat shock proteins and in vitro phosphorylation by different kinases

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Insights into the recognition and association of transmembrane alpha-helices. The free energy of alpha-helix dimerization in glycophorin A.

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Milestones in the Activation of a G Protein-Coupled Receptor. Insights from Molecular-Dynamics Simulations into the Human Cholecystokinin Receptor-1.

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21 January 2018

Protein stability and surface electrostatics: a charged relationship.

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Evaluation of Models of Electrostatic Interactions in Proteins

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Calculation of electrostatic potentials in an enzyme active site

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Rational Modification of Protein Stability by the Mutation of Charged Surface Residues†

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Designed TPR modules as novel anticancer agents

1 reference

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12 December 2020

based on heuristic

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Identifiers

10.1074/JBC.M109.033894

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19586912%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19586912%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19586912%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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