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(Q27647023)

English

2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead

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title
2-Amino-3,4-dihydroquinazolines as inhibitors of BACE-1 (beta-site APP cleaving enzyme): Use of structure based design to convert a micromolar hit into a nanomolar lead (English)
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author
Hans De Winter
object named as
Hans L De Winter
series ordinal
6
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Michael Parker
object named as
Michael H Parker
series ordinal
18
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author name string
Ellen W Baxter
series ordinal
1
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Kelly A Conway
series ordinal
2
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Ludo Kennis
series ordinal
3
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François Bischoff
series ordinal
4
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Marc H Mercken
series ordinal
5
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Charles H Reynolds
series ordinal
7
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Brett A Tounge
series ordinal
8
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Chi Luo
series ordinal
9
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Malcolm K Scott
series ordinal
10
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Yifang Huang
series ordinal
11
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Mirielle Braeken
series ordinal
12
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Serge M A Pieters
series ordinal
13
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Didier J C Berthelot
series ordinal
14
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Stefan Masure
series ordinal
15
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Wouter D Bruinzeel
series ordinal
16
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Alfonzo D Jordan
series ordinal
17
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Robert E Boyd
series ordinal
19
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Junya Qu
series ordinal
20
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Richard S Alexander
series ordinal
21
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Douglas E Brenneman
series ordinal
22
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Allen B Reitz
series ordinal
23
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publication date
6 September 2007
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volume
50
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issue
18
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page(s)
4261-4
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Identifiers

DOI
10.1021/JM0705408
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