(Q27647150)

1

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Christopher J Bond

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Lauren K Ely

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Jennifer Maynard

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K Christopher Garcia

The crystal structure of a T cell receptor in complex with peptide and MHC class II

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language of work or name

English

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publication date

September 2007

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published in

Nature Immunology

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volume

8

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issue

9

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page(s)

975-83

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cites work

1 reference

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

21 April 2017

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How a single T cell receptor recognizes both self and foreign MHC

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Structure of a covalently stabilized complex of a human alphabeta T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1

21 April 2017

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Crystal structure of a T cell receptor bound to an allogeneic MHC molecule

21 April 2017

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A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex

21 April 2017

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Structure of the complex between human T-cell receptor, viral peptide and HLA-A2

21 April 2017

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Two human T cell receptors bind in a similar diagonal mode to the HLA-A2/Tax peptide complex using different TCR amino acids

21 April 2017

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How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?

21 April 2017

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A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

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Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association

21 April 2017

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Coot: model-building tools for molecular graphics

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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How TCRs bind MHCs, peptides, and coreceptors

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MOLREP: an Automated Program for Molecular Replacement

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A correlation between TCR Valpha docking on MHC and CD8 dependence: implications for T cell selection

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The somatic generation of immune recognition

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The T cell repertoire may be biased in favor of MHC recognition.

21 January 2018

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The MHC reactivity of the T cell repertoire prior to positive and negative selection.

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Low Affinity Interaction of Peptide-MHC Complexes with T Cell Receptors

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How T cells 'see' antigen

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Two-step binding mechanism for T-cell receptor recognition of peptide MHC.

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How the T Cell Repertoire Becomes Peptide and MHC Specific

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Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide

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Tolerance and autoimmunity in TCR transgenic mice specific for myelin basic protein.

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Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention

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Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy

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Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: insights into MHC bias and antigen specificity

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Induction of apoptosis and T helper 2 (Th2) responses correlates with peptide affinity for the major histocompatibility complex in self-reactive T cell receptor transgenic mice

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Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

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High-level bacterial secretion of single-chain alphabeta T-cell receptors.

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Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis

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High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis

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Role of 2CT cell receptor residues in the binding of self- and allo-major histocompatibility complexes

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Identification of a crucial energetic footprint on the alpha1 helix of human histocompatibility leukocyte antigen (HLA)-A2 that provides functional interactions for recognition by tax peptide/HLA-A2-specific T cell receptors

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The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

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T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide

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Structure, function and properties of antibody binding sites

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Molecular recognition by a binary code

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Canonical structures for the hypervariable regions of T cell alphabeta receptors

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The T lymphocyte in experimental allergic encephalomyelitis

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7 January 2021

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

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Structural snapshot of aberrant antigen presentation linked to autoimmunity: the immunodominant epitope of MBP complexed with I-Au

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Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition

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Canonical structures for the hypervariable regions of immunoglobulins

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Pushing the boundaries of molecular replacement with maximum likelihood

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7 January 2021