(Q27647572)

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Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: a new specific binding mode to an a-minor motif enhances in vitro antibacterial activity

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scholarly article

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Crystal structure of the bacterial ribosomal decoding site complexed with a synthetic doubly functionalized paromomycin derivative: a new specific binding mode to an a-minor motif enhances in vitro antibacterial activity (English)

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crystal structure

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6

object named as

Eric Westhof

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Stephen Hanessian

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object named as

Stephen Hanessian

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Kandasamy Pachamuthu

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object named as

Kandasamy Pachamuthu

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Janek Szychowski

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object named as

Janek Szychowski

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author name string

Jiro Kondo

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Boris François

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publication date

November 2007

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2

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11

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1631-8

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Versatility of aminoglycosides and prospects for their future

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7 January 2021

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Molecular insights into aminoglycoside action and resistance

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7 January 2021

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RNA structure: reading the ribosome

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

7 January 2021

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Interaction of antibiotics with functional sites in 16S ribosomal RNA

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

7 January 2021

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Crystal structure of paromomycin docked into the eubacterial ribosomal decoding A site

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Crystal structure of a complex between the aminoglycoside tobramycin and an oligonucleotide containing the ribosomal decoding a site

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Crystal structure of geneticin bound to a bacterial 16S ribosomal RNA A site oligonucleotide

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Crystal structures of complexes between aminoglycosides and decoding A site oligonucleotides: role of the number of rings and positive charges in the specific binding leading to miscoding

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Molecular recognition by glycoside pseudo base pairs and triples in an apramycin-RNA complex

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Molecular recognition of RNA by neomycin and a restricted neomycin derivative.

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Recognition of cognate transfer RNA by the 30S ribosomal subunit

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Insights into the decoding mechanism from recent ribosome structures

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Selection of tRNA by the ribosome requires a transition from an open to a closed form

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Structural insights into translational fidelity

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Aminoglycosides: activity and resistance

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

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Bacterial resistance to aminoglycoside antibiotics

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The Molecular Basis for A‐Site Mutations Conferring Aminoglycoside Resistance: Relationship between Ribosomal Susceptibility and X‐ray Crystal Structures

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Antibacterial aminoglycosides with a modified mode of binding to the ribosomal-RNA decoding site

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Structure-based design, synthesis, and A-site rRNA cocrystal complexes of functionally novel aminoglycoside antibiotics: C2" ether analogues of paromomycin.

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The complex of a designer antibiotic with a model aminoacyl site of the 30S ribosomal subunit revealed by X-ray crystallography

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Crystal structure of the bacterial ribosomal decoding site complexed with amikacin containing the gamma-amino-alpha-hydroxybutyryl (haba) group

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

7 January 2021

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Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site

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The antibiotic viomycin traps the ribosome in an intermediate state of translocation.

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7 January 2021

based on heuristic

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New insights into aminoglycoside antibiotics and derivatives.

1 reference

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7 January 2021

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AMoRe: an automated package for molecular replacement

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

7 January 2021

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700113

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based on heuristic

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Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200700113

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based on heuristic

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Geometric nomenclature and classification of RNA base pairs

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https://api.crossref.org/works/10.1002%2FCMDC.200700113

7 January 2021

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Identifiers

10.1002/CMDC.200700113

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release_2nnoyw4dt5gxtokncz544vahty

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https://api.fatcat.wiki/v0/release/2nnoyw4dt5gxtokncz544vahty

24 November 2022

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