(Q27649162)

1

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Helga Raab

2

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Brent A Appleton

3

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Christopher J Bond

4

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Ping Wu

5

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Christian Wiesmann

6

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Sachdev S Sidhu

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

8 February 2008

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published in

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volume

283

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issue

6

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page(s)

3639-54

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cites work

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Domain antibodies: proteins for therapy

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Recognition of antigens by single-domain antibody fragments: the superfluous luxury of paired domains

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Naturally occurring antibodies devoid of light chains

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Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme

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Efficient targeting of conserved cryptic epitopes of infectious agents by single domain antibodies. African trypanosomes as paradigm

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Efficient tumor targeting by single-domain antibody fragments of camels

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Trials and tribulations: oncological antibody imaging comes to the fore

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Antigen specificity and high affinity binding provided by one single loop of a camel single-domain antibody

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The crystal structure of a llama heavy chain variable domain

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A single-domain antibody fragment in complex with RNase A: non-canonical loop structures and nanomolar affinity using two CDR loops

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Camelid heavy-chain variable domains provide efficient combining sites to haptens

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Lateral recognition of a dye hapten by a llama VHH domain

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Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology

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Camel heavy-chain antibodies: diverse germline V(H)H and specific mechanisms enlarge the antigen-binding repertoire

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'Camelising' human antibody fragments: NMR studies on VH domains.

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Rearrangement of the former VL interface in the solution structure of a camelised, single antibody VH domain

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Antibody VH domains as small recognition units

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Affinity selection of a camelized V(H) domain antibody inhibitor of hepatitis C virus NS3 protease

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Contributions of CDR3 to V H H domain stability and the design of monobody scaffolds for naive antibody libraries

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Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli

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Crystal structure of HEL4, a soluble, refoldable human V(H) single domain with a germ-line scaffold

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Solution structure of a llama single-domain antibody with hydrophobic residues typical of the VH/VL interface

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Single domain antibodies: comparison of camel VH and camelised human VH domains

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Selection of human anti-hapten antibodies from semisynthetic libraries

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Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.

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High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold

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High copy display of large proteins on phage for functional selections

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Phage display for selection of novel binding peptides

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Rapid mapping of protein functional epitopes by combinatorial alanine scanning

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A structure-based database of antibody variable domain diversity.

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Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Using circular dichroism collected as a function of temperature to determine the thermodynamics of protein unfolding and binding interactions

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Processing of X-ray diffraction data collected in oscillation mode

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Likelihood-enhanced fast translation functions

21 January 2018

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Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

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Refinement of macromolecular structures by the maximum-likelihood method

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Coot: model-building tools for molecular graphics

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Humanization of an anti-p185HER2 antibody for human cancer therapy

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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Untangling the ErbB signalling network

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Trastuzumab and breast cancer: developments and current status

21 January 2018

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X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling

21 January 2018

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High level Escherichia coli expression and production of a bivalent humanized antibody fragment

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Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions

21 January 2018

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Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment

21 January 2018

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Antibody variable region binding by Staphylococcal protein A: thermodynamic analysis and location of the Fv binding site on E-domain

21 January 2018

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Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: structural basis for recognition of B-cell receptors and superantigen activity

21 January 2018

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Staphylococcal protein A binding to VH3 encoded immunoglobulins

21 January 2018

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Antibody arrays for high-throughput screening of antibody-antigen interactions

21 January 2018

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Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure

21 January 2018

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Antigen binding thermodynamics and antiproliferative effects of chimeric and humanized anti-p185HER2 antibody Fab fragments

21 January 2018

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Thermodynamic analysis of an antibody functional epitope

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M708536200

Biophysical Properties of Camelid VHHDomains Compared to Those of Human VH3 Domains†

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M708536200

Different Equilibrium Stability Behavior of ScFv Fragments: Identification, Classification, and Improvement by Protein Engineering†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M708536200