(Q27653053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19054767%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Crystal structure and catalysis of the selenoprotein thioredoxin reductase 1 (English)

1 reference

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18 January 2020

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2

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18 January 2020

Ylva Lindqvist

3

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18 January 2020

Qing Cheng

1

1 reference

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18 January 2020

Elias Arnér

4

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18 January 2020

author name string

Elias S J Arnér

4

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language of work or name

English

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publication date

3 December 2008

1 reference

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Journal of Biological Chemistry

18 January 2020

published in

1 reference

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18 January 2020

volume

284

1 reference

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18 January 2020

issue

6

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18 January 2020

page(s)

3998-4008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19054767%20AND%20SRC:MED&resulttype=core&format=json

Selenium, the element of the moon, in life on earth

18 January 2020

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The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

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Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development

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Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function

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The refined structure of the selenoenzyme glutathione peroxidase at 0.2-nm resolution

21 January 2018

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Physiological functions of thioredoxin and thioredoxin reductase

21 January 2018

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The thioredoxin system—From science to clinic

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21 January 2018

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Selenocysteine, identified as the penultimate C-terminal residue in human T-cell thioredoxin reductase, corresponds to TGA in the human placental gene

21 January 2018

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A new selenoprotein from human lung adenocarcinoma cells: purification, properties, and thioredoxin reductase activity

21 January 2018

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The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli

21 January 2018

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Mammalian thioredoxin reductase: oxidation of the C-terminal cysteine/selenocysteine active site forms a thioselenide, and replacement of selenium with sulfur markedly reduces catalytic activity

21 January 2018

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Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations

21 January 2018

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Structure and mechanism of mammalian thioredoxin reductase: the active site is a redox-active selenolthiol/selenenylsulfide formed from the conserved cysteine-selenocysteine sequence

21 January 2018

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Rat and calf thioredoxin reductase are homologous to glutathione reductase with a carboxyl-terminal elongation containing a conserved catalytically active penultimate selenocysteine residue.

21 January 2018

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Three-dimensional structure of a mammalian thioredoxin reductase: implications for mechanism and evolution of a selenocysteine-dependent enzyme

21 January 2018

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Semisynthesis and characterization of mammalian thioredoxin reductase

21 January 2018

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Investigation of the C-terminal redox center of high-Mr thioredoxin reductase by protein engineering and semisynthesis

21 January 2018

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Structural and Biochemical Studies Reveal Differences in the Catalytic Mechanisms of Mammalian and Drosophila melanogaster Thioredoxin Reductases †

21 January 2018

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Crystal structures of oxidized and reduced mitochondrial thioredoxin reductase provide molecular details of the reaction mechanism

21 January 2018

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The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis

21 January 2018

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Interactions of quinones with thioredoxin reductase: a challenge to the antioxidant role of the mammalian selenoprotein

21 January 2018

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Interactions of nitroaromatic compounds with the mammalian selenoprotein thioredoxin reductase and the relation to induction of apoptosis in human cancer cells

21 January 2018

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Active sites of thioredoxin reductases: why selenoproteins?

21 January 2018

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Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds

21 January 2018

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Studies of an active site mutant of the selenoprotein thioredoxin reductase: the Ser-Cys-Cys-Ser motif of the insect orthologue is not sufficient to replace the Cys-Sec dyad in the mammalian enzyme.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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The functional role of selenocysteine (Sec) in the catalysis mechanism of large thioredoxin reductases: proposition of a swapping catalytic triad including a Sec-His-Glu state

21 January 2018

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NMR structure of oxidized glutaredoxin 3 from Escherichia coli

21 January 2018

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Mutational analysis of the BPTI folding pathway: I. Effects of aromatic-->leucine substitutions on the distribution of folding intermediates

21 January 2018

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Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells

21 January 2018

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Rapid induction of cell death by selenium-compromised thioredoxin reductase 1 but not by the fully active enzyme containing selenocysteine

21 January 2018

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Selenolthiol and dithiol C-terminal tetrapeptide motifs for one-step purification and labeling of recombinant proteins produced in E. coli.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M807068200

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19054767%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017