(Q27653362)

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Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA

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scholarly article

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Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA (English)

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Staphylococcus aureus

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based on heuristic

inferred from title

4

object named as

Glenn W Kaatz

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author name string

Muthiah Kumaraswami

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Jason T Schuman

2

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Susan M Seo

3

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Richard G Brennan

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language of work or name

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publication date

March 2009

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Nucleic Acids Research

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37

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4

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1211-24

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The crystal structure of MexR from Pseudomonas aeruginosa in complex with its antirepressor ArmR

1 reference

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20 March 2017

Structural insight on the mechanism of regulation of the MarR family of proteins: high-resolution crystal structure of a transcriptional repressor from Methanobacterium thermoautotrophicum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

20 March 2017

Structural mechanism of organic hydroperoxide induction of the transcription regulator OhrR

1 reference

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20 March 2017

Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus

1 reference

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20 March 2017

Crystal Structures of Multidrug Binding Protein TtgR in Complex with Antibiotics and Plant Antimicrobials

1 reference

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20 March 2017

Crystal structure of the MexR repressor of the mexRAB-oprM multidrug efflux operon of Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

20 March 2017

Structural mechanisms of QacR induction and multidrug recognition

1 reference

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20 March 2017

The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

20 March 2017

Crystal structure of the transcription activator BmrR bound to DNA and a drug

1 reference

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20 March 2017

CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

1 reference

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20 March 2017

The integration of macromolecular diffraction data

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

1 reference

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20 March 2017

The CCP4 suite: programs for protein crystallography

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

20 March 2017

Preparation of selenomethionyl proteins for phase determination

1 reference

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20 March 2017

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1 reference

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20 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

7 April 2017

Winged helix proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

7 April 2017

MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Regulation of virulence by members of the MarR/SlyA family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Ligand-responsive transcriptional regulation by members of the MarR family of winged helix proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Efflux systems in bacterial pathogens: an opportunity for therapeutic intervention? An industry view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Antibiotic resistance in Staphylococcus aureus and its relevance in therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Molecular determinants of the hpa regulatory system of Escherichia coli: the HpaR repressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Structural mechanisms of multidrug recognition and regulation by bacterial multidrug transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Multidrug resistance: can different keys open the same lock?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Prokaryotic transcription regulators: more than just the helix-turn-helix motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

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Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Bacterial antibiotic efflux systems of medical importance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

The EmrR protein represses the Escherichia coli emrRAB multidrug resistance operon by directly binding to its promoter region.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Reciprocal-space solvent flattening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Purification and ligand binding of EmrR, a regulator of a multidrug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Discrimination of solvent from protein regions in native Fouriers as a means of evaluating heavy-atom solutions in the MIR and MAD methods

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

29 September 2017

Resistance to antibiotics mediated by target alterations

1 reference

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29 September 2017

Prevention of drug access to bacterial targets: permeability barriers and active efflux

1 reference

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29 September 2017

A novel MATE family efflux pump contributes to the reduced susceptibility of laboratory-derived Staphylococcus aureus mutants to tigecycline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2651776

2 June 2018

Multidrug efflux pump overexpression in Staphylococcus aureus after single and multiple in vitro exposures to biocides and dyes

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKN1046

21 January 2018

Negative cooperativity of uric acid binding to the transcriptional regulator HucR from Deinococcus radiodurans

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKN1046

21 January 2018

Structure of an OhrR-ohrA operator complex reveals the DNA binding mechanism of the MarR family

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKN1046

21 January 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19129225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antimicrobial resistance in gram-positive bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of an archaeal homologue of multidrug resistance repressor protein, EmrR, from hyperthermophilic archaea Sulfolobus tokodaii strain 7

1 reference

https://pubmed.ncbi.nlm.nih.gov/19129225

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/GKN1046

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