(Q27653637)

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Influence of naturally-occurring 5â ²-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: An X-ray crystallographic study

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scholarly article

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20 January 2020

Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study (English)

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20 January 2020

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organic chemistry

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Daniel E. Holloway

1

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20 January 2020

Demetres D. Leonidas

3

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20 January 2020

K. Ravi Acharya

5

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20 January 2020

author name string

Gayatri B Chavali

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20 January 2020

Matthew D Baker

4

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20 January 2020

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1 December 2009

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20 January 2020

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20 January 2020

91

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20 January 2020

995-1008

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20 January 2020

12

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20 January 2020

Ribonuclease A Homologues of the Zebrafish: Polymorphism, Crystal Structures of Two Representatives and their Evolutionary Implications

1 reference

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20 March 2017

RNA backbone: consensus all-angle conformers and modular string nomenclature (an RNA Ontology Consortium contribution)

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

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The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories

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20 March 2017

High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors

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20 March 2017

The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site

1 reference

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20 March 2017

Cleavage of 3',5'-pyrophosphate-linked dinucleotides by ribonuclease A and angiogenin

1 reference

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20 March 2017

Binding of phosphate and pyrophosphate ions at the active site of human angiogenin as revealed by X-ray crystallography

1 reference

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20 March 2017

Mapping the ribonucleolytic active site of eosinophil-derived neurotoxin (EDN). High resolution crystal structures of EDN complexes with adenylic nucleotide inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816359

20 March 2017

Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816359

20 March 2017

Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816359

20 March 2017

Crystal structure of human angiogenin reveals the structural basis for its functional divergence from ribonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816359

20 March 2017

Crystal structure of ribonuclease A.d(ApTpApApG) complex. Direct evidence for extended substrate recognition

1 reference

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20 March 2017

Site-directed mutagenesis of histidine-13 and histidine-114 of human angiogenin. Alanine derivatives inhibit angiogenin-induced angiogenesis

1 reference

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20 March 2017

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

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20 March 2017

Coot: model-building tools for molecular graphics

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20 March 2017

Refinement of macromolecular structures by the maximum-likelihood method

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20 March 2017

The CCP4 suite: programs for protein crystallography

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20 March 2017

SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model

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20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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20 March 2017

Satisfying hydrogen bonding potential in proteins

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20 March 2017

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20 March 2017

A combined kinetic and modeling study of the catalytic center subsites of human angiogenin

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29 September 2017

An introduction to stereochemical restraints

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29 September 2017

The new CCP4 Coordinate Library as a toolkit for the design of coordinate-related applications in protein crystallography.

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29 September 2017

RNA backbone is rotameric

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29 September 2017

A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity.

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29 September 2017

Eosinophils, eosinophil ribonucleases, and their role in host defense against respiratory virus pathogens.

1 reference

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29 September 2017

Small molecule inhibitors of RNase A and related enzymes

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29 September 2017

Three-dimensional structure of the complexes of ribonuclease A with 2',5'-CpA and 3',5'-d(CpA) in aqueous solution, as obtained by NMR and restrained molecular dynamics

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29 September 2017

Alteration of the enzymatic specificity of human angiogenin by site-directed mutagenesis

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29 September 2017

The structures of RNase A complexed with 3'-CMP and d(CpA): active site conformation and conserved water molecules

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29 September 2017

Structure and function of ribonuclease A binding subsites

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29 September 2017

Isolation and identification of 2′-phosphoadenosine diphosphate, an alkali-degradation product of nicotinamide adenine dinucleotide phosphate

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29 September 2017

Conservation of mus-ms enzyme motions in the apo- and substrate-mimicked state

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2 June 2018

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2 June 2018

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21 January 2018

Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2816359

27 November 2018

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27 November 2018

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27 November 2018

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27 November 2018

Inhibition of mammalian ribonucleases by endogenous adenosine dinucleotides.

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27 November 2018

Potent inhibition of mammalian ribonucleases by 3', 5'-pyrophosphate-linked nucleotides

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1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The stability of pyridine nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eosinophil-derived neurotoxin and human liver ribonuclease. Identity of structure and linkage of neurotoxicity to nuclease activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of phosphate ligands to ribonuclease A

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conformational analysis of the sugar ring in nucleosides and nucleotides. New description using the concept of pseudorotation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IUPAC-IUB Joint Commission on Biochemical Nomenclature (JCBN). Abbreviations and symbols for the description of conformations of polynucleotide chains. Recommendations 1982

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

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5'-Diphosphoadenosine 3'-phosphate is a potent inhibitor of bovine pancreatic ribonuclease A

1 reference

https://pubmed.ncbi.nlm.nih.gov/19191310

12 December 2020

based on heuristic

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Identifiers

10.1002/BIP.21158

1 reference

Europe PubMed Central

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20 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19191310%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

Europe PubMed Central

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20 January 2020

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