(Q27653671)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Rational stabilization of enzymes by computational redesign of surface charge-charge interactions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Mayank M Patel

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Jiajing Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Scott A McCallum

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Chunyu Wang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

George I Makhatadze

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

5 February 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

2601-2606

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

The Pfam protein families database

20 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

High-resolution structural and thermodynamic analysis of extreme stabilization of human procarboxypeptidase by computational protein design

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Design, structure and stability of a hyperthermophilic protein variant

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Crystal structure of common type acylphosphatase from bovine testis

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Comparative protein structure modeling of genes and genomes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Protein backbone angle restraints from searching a database for chemical shift and sequence homology

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

How enzymes adapt: lessons from directed evolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Removal of surface charge-charge interactions from ubiquitin leaves the protein folded and very stable

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Insights into acylphosphatase structure and catalytic mechanism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Classical electrostatics in biology and chemistry

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

On the relationship between thermal stability and catalytic power of enzymes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Computational design of the Fyn SH3 domain with increased stability through optimization of surface charge charge interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Elimination of the C-cap in ubiquitin - structure, dynamics and thermodynamic consequences.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Effects of charge-to-alanine substitutions on the stability of ribosomal protein L30e from Thermococcus celer.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Electrostatics in computational protein design

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Cdc42: new roads to travel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Combining conformational flexibility and continuum electrostatics for calculating pK(a)s in proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

De novo design of biocatalysts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

THEMATICS: a simple computational predictor of enzyme function from structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Review: protein design--where we were, where we are, where we're going.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

To charge or not to charge?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Functions and functional domains of the GTPase Cdc42p

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Increasing protein stability by altering long-range coulombic interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Automated combined assignment of NOESY spectra and three-dimensional protein structure determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Electrostatic and hydrodynamic orientational steering effects in enzyme-substrate association

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

A new synthesis of benzoyl phosphate: A substrate for acyl phosphatase assay

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Computational thermostabilization of an enzyme

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Engineering a thermostable protein via optimization of charge-charge interactions on the protein surface

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2650310

Protein stability and surface electrostatics: a charged relationship.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

How to improve nature: study of the electrostatic properties of the surface of alpha-lactalbumin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Mechanism of thermostabilization in a designed cold shock protein with optimized surface electrostatic interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Electrostatic channeling of substrates between enzyme active sites: comparison of simulation and experiment

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Electrostatic effects in macromolecules: fundamental concepts and practical modeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Biochemical studies of the mechanism of action of the Cdc42-GTPase-activating protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

A captured folding intermediate involved in dimerization and domain-swapping of GB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Protein stabilization by the rational design of surface charge-charge interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0808220106

Aromatic acyl phosphates as substrates of acyl phosphatase

21 January 2018

1 reference

12 December 2020

Calculation of electrostatic interactions in proteins

1 reference

12 December 2020

Fluoride activation of the Rho family GTP-binding protein Cdc42Hs

1 reference

12 December 2020

Thermal versus guanidine-induced unfolding of ubiquitin. An analysis in terms of the contributions from charge-charge interactions to protein stability

1 reference

12 December 2020

Rational Modification of Protein Stability by the Mutation of Charged Surface Residues†

1 reference

12 December 2020

Role of the charge-charge interactions in defining stability and halophilicity of the CspB proteins

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0808220106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19196981%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

19196981

1 reference