(Q27653751)

English

Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity

scientific article

In more languages

Statements

scholarly article

0 references

Increased hydrophobic interactions of iclaprim with Staphylococcus aureus dihydrofolate reductase are responsible for the increase in affinity and antibacterial activity (English)

0 references

1 reference

based on heuristic

inferred from title

Staphylococcus aureus

1 reference

based on heuristic

inferred from title

author name string

Christian Oefner

1

0 references

Monica Bandera

2

0 references

Andreas Haldimann

3

0 references

Heike Laue

4

0 references

Henk Schulz

5

0 references

Seema Mukhija

6

0 references

Sandro Parisi

7

0 references

Laurent Weiss

8

0 references

Sergio Lociuro

9

0 references

Glenn E Dale

10

0 references

language of work or name

0 references

publication date

April 2009

0 references

Journal of Antimicrobial Chemotherapy

0 references

63

0 references

4

0 references

687-98

0 references

DNA and RNA synthesis: antifolates

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Antimicrobial dihydrofolate reductase inhibitors--achievements and future options: review

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Dihydrofolate reductase inhibitors as antibacterial agents

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Structure, dynamics, and catalytic function of dihydrofolate reductase

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Trimethoprim-sulfamethoxazole as a viable treatment option for infections caused by methicillin-resistant Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Trimethoprim-sulfamethoxazole revisited

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

The growing menace of community-acquired methicillin-resistant Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Resistance to antibiotics: are we in the post-antibiotic era?

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Antimicrobial resistance: current status and future direction

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Frequency and Transferability of Trimethoprim and Sulfonamide Resistance in Methicillin-ResistantStaphylococcus aureusandStaphylococcus epidermidis

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Susceptibility of Staphylococcus aureus isolated from skin and wound infections in the United States 2005-07: laboratory-based surveillance study

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Cloning and characterization of a novel, plasmid-encoded trimethoprim-resistant dihydrofolate reductase from Staphylococcus haemolyticus MUR313.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Trimethoprim resistance transposon Tn4003 from Staphylococcus aureus encodes genes for a dihydrofolate reductase and thymidylate synthetase flanked by three copies of IS257.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Cloning and characterization of a novel trimethoprim-resistant dihydrofolate reductase from a nosocomial isolate of Staphylococcus aureus CM.S2 (IMCJ1454).

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Mechanism of action of purpuromycin

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Isothermal titration calorimetry to determine association constants for high-affinity ligands.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Reversal of activity of trimethoprim against gram-positive cocci by thymidine, thymine and 'folates'.

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Trimethoprim: laboratory and clinical studies

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Structure and function of the dihydropteroate synthase from Staphylococcus aureus

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

In vitro activity of the novel diaminopyrimidine, iclaprim, in combination with folate inhibitors and other antimicrobials with different mechanisms of action

1 reference

https://api.crossref.org/works/10.1093%2FJAC%2FDKP024

21 January 2018

Identifiers

10.1093/JAC/DKP024

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q27653751&oldid=1387829535"