(Q27654019)

22 June 2017

title

Characterization of IgG1 conformation and conformational dynamics by hydrogen/deuterium exchange mass spectrometry (English)

1 reference

22 June 2017

0 references

John R Engen

5

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author name string

Damian Houde

1

1 reference

22 June 2017

Joseph Arndt

2

1 reference

22 June 2017

Wayne Domeier

3

1 reference

22 June 2017

Steven Berkowitz

4

1 reference

22 June 2017

language of work or name

English

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publication date

1 April 2009

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22 June 2017

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22 June 2017

volume

81

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22 June 2017

issue

7

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22 June 2017

page(s)

2644-2651

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Crowded, cell-like environment induces shape changes in aspherical protein

22 June 2017

cites work

1 reference

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20 March 2017

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Structural comparison of fucosylated and nonfucosylated Fc fragments of human immunoglobulin G1

20 March 2017

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20 March 2017

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20 March 2017

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1.9 A structure of the therapeutic antibody CAMPATH-1H fab in complex with a synthetic peptide antigen

20 March 2017

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Crystallographic structure of an intact IgG1 monoclonal antibody

20 March 2017

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Refined structure of an intact IgG2a monoclonal antibody

20 March 2017

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Three-dimensional structure of a human immunoglobulin with a hinge deletion

20 March 2017

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Determination of amide hydrogen exchange by mass spectrometry: a new tool for protein structure elucidation

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Calculation of protein extinction coefficients from amino acid sequence data

20 March 2017

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Hydrogen exchange mass spectrometry for the analysis of protein dynamics

20 March 2017

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Hydrogen exchange and structural dynamics of proteins and nucleic acids

20 March 2017

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20 March 2017

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Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.

29 September 2017

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Hydrogen/deuterium exchange-mass spectrometry: a powerful tool for probing protein structure, dynamics and interactions.

29 September 2017

1 reference

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The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data

29 September 2017

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Development trends for monoclonal antibody cancer therapeutics.

29 September 2017

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Semi-automated data processing of hydrogen exchange mass spectra using HX-Express

29 September 2017

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Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis

29 September 2017

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Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry

29 September 2017

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Protein conformations, interactions, and H/D exchange

29 September 2017

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Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy.

29 September 2017

1 reference

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Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition

29 September 2017

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Influence of macromolecular crowding upon the stability and state of association of proteins: predictions and observations

29 September 2017

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Rapid analysis of protein structure and dynamics by hydrogen/deuterium exchange mass spectrometry.

29 September 2017

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The unfolding/denaturation of immunogammaglobulin of isotype 2b and its F(ab) and F(c) fragments

29 September 2017

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Investigating the higher order structure of proteins. Hydrogen exchange, proteolytic fragmentation, and mass spectrometry

29 September 2017

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Antibody humanization: a case of the 'Emperor's new clothes'?

29 September 2017

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Probing the non-covalent structure of proteins by amide hydrogen exchange and mass spectrometry

29 September 2017

1 reference

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Detection of transient protein folding populations by mass spectrometry

29 September 2017

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Application of 13C NMR spectroscopy to paratope mapping for larger antigen-Fab complexes

29 September 2017

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Characterization of IgG1 immunoglobulins and peptide-Fc fusion proteins by limited proteolysis in conjunction with LC-MS.

2 June 2018

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Structure determinations of human and chimaeric antibodies by solution scattering and constrained molecular modelling.

27 November 2018

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Reversed-phase liquid chromatography-mass spectrometry of site-specific chemical modifications in intact immunoglobulin molecules and their fragments

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779575

Characterization of variable regions of monoclonal antibodies by top-down mass spectrometry.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779575

Identification of cysteinylation of a free cysteine in the Fab region of a recombinant monoclonal IgG1 antibody using Lys-C limited proteolysis coupled with LC/MS analysis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779575

Empowering the inventor--the case of monoclonal antibodies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2779575

A universal algorithm for fast and automated charge state deconvolution of electrospray mass-to-charge ratio spectra.

27 November 2018

1 reference

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Comparison of methionine oxidation in thermal stability and chemically stressed samples of a fully human monoclonal antibody

27 November 2018

1 reference

12 December 2020

Analysis of recombinant monoclonal antibody isoforms by electrospray ionization mass spectrometry as a strategy for streamlining characterization of recombinant monoclonal antibody charge heterogeneity

1 reference

12 December 2020

Effect of posttranslational modifications on the thermal stability of a recombinant monoclonal antibody

1 reference

12 December 2020

Hydrogen exchange-mass spectrometry: optimization of digestion conditions

1 reference

12 December 2020

Identifiers

DOI

10.1021/AC802575Y

1 reference

OpenCitations bibliographic resource ID

22 June 2017

1338962

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1338962

1 reference