(Q27654155)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Antibodies specifically targeting a locally misfolded region of tumor associated EGFR (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

4

1 reference

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23 January 2020

Suzanne G Orchard

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Timothy E Adams

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Walter D Fairlie

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Shenggen Yao

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Andrew M Scott

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Terrance G Johns

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

15

Gerd Ritter

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

13

Lloyd J Old

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

14

Elisabeth Stockert

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2

Antony W Burgess

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

5

Glenn Cartwright

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

6

Francesca Walker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

9

Edouard C Nice

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

10

Julie Rothacker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

12

Webster K Cavenee

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

17

Peter A Hoyne

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

18

Dane Wittrup

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

20

Jennifer R Cochran

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

author name string

Thomas P J Garrett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Hui K Gan

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Andrew H A Clayton

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Bruno Catimel

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Ginger Chao

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Cindy Luo

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Mezhen Lou

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Trevor Huyton

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Yibin Xu

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

16 March 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

23 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

5082-5087

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

Matuzumab Binding to EGFR Prevents the Conformational Rearrangement Required for Dimerization

23 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

EGFR family: structure physiology signalling and therapeutic targets

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Rash from EGFR inhibitors: opportunities and challenges for palliation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Structure-based view of epidermal growth factor receptor regulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

EGFR-targeting drugs in combination with cytotoxic agents: from bench to bedside, a contrasted reality

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

A phase I clinical trial with monoclonal antibody ch806 targeting transitional state and mutant epidermal growth factor receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Epidermal growth factor receptor targeting in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Nondermatologic adverse events associated with anti-EGFR therapy.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Fine epitope mapping of anti-epidermal growth factor receptor antibodies through random mutagenesis and yeast surface display

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Disulfide bonds as switches for protein function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Therapeutic potential of ABX-EGF: a fully human anti-epidermal growth factor receptor monoclonal antibody for cancer treatment

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

IMC-C225, an anti-epidermal growth factor receptor monoclonal antibody, for treatment of head and neck cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Unarmed, tumor-specific monoclonal antibody effectively treats brain tumors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Biochemical characterization of mutant EGF receptors expressed in the hemopoietic cell line BaF/3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Expression of mRNA for epidermal growth factor, transforming growth factor-alpha and their receptor in human prostate tissue and cell lines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2656555

Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

Structural model of the mAb 806-EGFR complex using computational docking followed by computational and experimental mutagenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

An automated peptide and protein thiazolidine coupling chemistry for biosensor immobilization giving a unique N-terminal orientation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

Spherically averaged phased translation function and its application to the search for molecules and fragments in electron-density maps

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811559106

21 January 2018

Identifiers

DOI

10.1073/PNAS.0811559106

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

0 references

release_a54kgidiuzabtaq6mizpzwj4kq

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/a54kgidiuzabtaq6mizpzwj4kq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19289842%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

2 references