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The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
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scholarly article
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title
The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing
(English)
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main subject
gene silencing
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Gawky Dmel_CG31992
1 reference
stated in
GOA release 2020-03-11
author
Elisa Izaurralde
series ordinal
5
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Oliver Weichenrieder
series ordinal
4
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Ana Eulalio
series ordinal
1
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Regina Büttner
series ordinal
3
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Felix Tritschler
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Vincent Truffault
series ordinal
6
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language of work or name
English
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publication date
May 2009
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published in
Nucleic Acids Research
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volume
37
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page(s)
2974-83
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issue
9
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cites work
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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes
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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing
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The GW182 protein colocalizes with mRNA degradation associated proteins hDcp1 and hLSm4 in cytoplasmic GW bodies
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A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles
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20 March 2017
Protein backbone angle restraints from searching a database for chemical shift and sequence homology
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A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain
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Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins
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29 September 2017
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29 September 2017
Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing
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29 September 2017
GW182 family proteins are crucial for microRNA-mediated gene silencing
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29 September 2017
MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.
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29 September 2017
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29 September 2017
NMR structure of the three quasi RNA recognition motifs (qRRMs) of human hnRNP F and interaction studies with Bcl-x G-tract RNA: a novel mode of RNA recognition
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29 September 2017
Extended flip-back schemes for sensitivity enhancement in multidimensional HSQC-type out-and-back experiments
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29 September 2017
P-body formation is a consequence, not the cause, of RNA-mediated gene silencing
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2 June 2018
An efficient strategy for assignment of cross-peaks in 3D heteronuclear NOESY experiments.
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27 November 2018
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay
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27 November 2018
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans
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27 November 2018
Identifiers
DOI
10.1093/NAR/GKP173
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PMCID
2685099
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PubMed ID
19295135
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ResearchGate publication ID
41813760
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