(Q46698175)

24 December 2017

title

GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay (English)

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24 December 2017

main subject

Gawky Dmel_CG31992

1 reference

GOA release 2020-03-11

author

Elisa Izaurralde

series ordinal

3

1 reference

24 December 2017

Ana Eulalio

object named as

Ana Eulalio

series ordinal

1

0 references

Eric Huntzinger

series ordinal

2

object named as

Eric Huntzinger

1 reference

24 December 2017

16 March 2008

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24 December 2017

Nature Structural & Molecular Biology

published in

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24 December 2017

volume

15

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24 December 2017

page(s)

346-353

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24 December 2017

issue

4

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24 December 2017

https://scigraph.springernature.com/pub.10.1038/nsmb.1405

exact match

0 references

1 reference

Mechanisms of microRNA-mediated gene regulation in animal cells

31 March 2020

1 reference

Repression of protein synthesis by miRNAs: how many mechanisms?

31 March 2020

1 reference

Getting to the root of miRNA-mediated gene silencing

31 March 2020

1 reference

MicroRNA silencing through RISC recruitment of eIF6

31 March 2020

1 reference

Release of eIF6 (p27BBP) from the 60S subunit allows 80S ribosome assembly

31 March 2020

1 reference

The Saccharomyces cerevisiae TIF6 gene encoding translation initiation factor 6 is required for 60S ribosomal subunit biogenesis

31 March 2020

1 reference

Sen34p depletion blocks tRNA splicing in vivo and delays rRNA processing

31 March 2020

1 reference

An mRNA m7G cap binding-like motif within human Ago2 represses translation

31 March 2020

1 reference

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

31 March 2020

1 reference

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

31 March 2020

1 reference

Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells

31 March 2020

1 reference

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

31 March 2020

1 reference

MicroRNAs silence gene expression by repressing protein expression and/or by promoting mRNA decay.

31 March 2020

1 reference

Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs

31 March 2020

1 reference

Differential regulation of germline mRNAs in soma and germ cells by zebrafish miR-430.

31 March 2020

1 reference

Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster

31 March 2020

1 reference

MicroRNAs direct rapid deadenylation of mRNA

31 March 2020

1 reference

Target-specific requirements for enhancers of decapping in miRNA-mediated gene silencing

31 March 2020

1 reference

A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

31 March 2020

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Tethering of human Ago proteins to mRNA mimics the miRNA-mediated repression of protein synthesis

31 March 2020

1 reference

MIWI associates with translational machinery and PIWI-interacting RNAs (piRNAs) in regulating spermatogenesis

31 March 2020

1 reference

The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans.

31 March 2020

1 reference

Disruption of GW bodies impairs mammalian RNA interference

31 March 2020

1 reference

A role for the P-body component GW182 in microRNA function

31 March 2020

1 reference

Identification of novel argonaute-associated proteins

31 March 2020

1 reference

Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54

31 March 2020

1 reference

Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.

31 March 2020

1 reference

A conserved motif in Argonaute-interacting proteins mediates functional interactions through the Argonaute PIWI domain

31 March 2020

1 reference

Slicer and the argonautes

31 March 2020

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Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.

31 March 2020

1 reference

Inhibition of translational initiation by Let-7 MicroRNA in human cells

31 March 2020

1 reference

MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function

31 March 2020

1 reference

Recapitulation of short RNA-directed translational gene silencing in vitro

31 March 2020

1 reference

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.1405

1 reference

24 December 2017

PubMed ID

18345015

1 reference

24 December 2017