(Q27654656)

1

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Gregor Blaha

2

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Peter B Moore

3

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Thomas A Steitz

Journal of Molecular Biology

4

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language of work or name

English

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publication date

29 May 2009

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published in

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volume

389

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issue

1

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page(s)

146-56

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cites work

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

1 reference

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Crystal structure of the oxazolidinone antibiotic linezolid bound to the 50S ribosomal subunit

20 March 2017

1 reference

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Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

20 March 2017

1 reference

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Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity

20 March 2017

1 reference

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The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole

20 March 2017

1 reference

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Structures of five antibiotics bound at the peptidyl transferase center of the large ribosomal subunit

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

The structures of four macrolide antibiotics bound to the large ribosomal subunit

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

High resolution structure of the large ribosomal subunit from a mesophilic eubacterium

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

20 March 2017

1 reference

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The structural basis of ribosome activity in peptide bond synthesis

20 March 2017

1 reference

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The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Structure of the 70S ribosome complexed with mRNA and tRNA

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Structures of the bacterial ribosome at 3.5 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

The interpretation of protein structures: Estimation of static accessibility

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Inhibition of Translation in Eukaryotic Systems by Harringtonine

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Antibiotic Substances From Basidiomycetes: VIII. Pleurotus Multilus (Fr.) Sacc. and Pleurotus Passeckerianus Pilat

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Antibiotics and the ribosome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Species-specific antibiotic-ribosome interactions: implications for drug development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Studies on the mechanism of action of chloramphenicol. I. The conformation of chlioramphenicol in solution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Homoharringtonine: history, current research, and future direction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Ribosomal binding region for the antibiotic tiamulin: stoichiometry, subunit location, and affinity for various analogs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Antimicrobial activities of 81.723 hfu, a new pleuromutilin derivative

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Inhibitors of Protein Biosynthesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Bruceantin, a novel inhibitor of peptide bond formation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

A 9 A resolution X-ray crystallographic map of the large ribosomal subunit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Amino Acylaminonucleoside Inhibitors of Protein Synthesis. The Effect of Amino Acyl Ribonucleic Acid on the Inhibition*

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

The Mode of Action of Pleuromutilin Derivatives. Effect on Cell-Free Polypeptide Synthesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Insensitivity of archaebacterial ribosomes to protein synthesis inhibitors. Evolutionary implications

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Structural insights into the roles of water and the 2' hydroxyl of the P site tRNA in the peptidyl transferase reaction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

The roles of ribosomal proteins in the structure assembly, and evolution of the large ribosomal subunit

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682339

The Mode of Action of Pleuromutilin Derivatives. Location and Properties of the Pleuromutilin Binding Site on Escherichia coli Ribosomes

27 November 2018

1 reference

12 December 2020

Harringtonine, an inhibitor of initiation of protein biosynthesis

1 reference

12 December 2020

Mode of action of the antitumor compound bruceantin, an inhibitor of protein synthesis

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

Antitumor Alkaloids from Cephalotaxus harringtonia: Structure and Activity

1 reference

12 December 2020

On the mechanism of action of chloramphenicol in protein synthesis

1 reference

12 December 2020

10.1016/J.JMB.2009.04.005

Identifiers

DOI

1 reference

release_dg4wm3b6c5dtnniwq7crmglppm

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

19362093

1 reference