(Q27655620)

1

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Martin J Andrews

2

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Campbell McInnes

3

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Andy Plater

4

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Lorraine Innes

5

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Scott Renachowski

6

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Angela Cowan

7

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Peter M Fischer

Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation

8

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language of work or name

1 reference

July 2009

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published in

ChemMedChem

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volume

4

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issue

7

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page(s)

1120-8

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cites work

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

Cyclin B and cyclin A confer different substrate recognition properties on CDK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

Principles of CDK regulation

21 January 2018

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7 January 2021

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Peptidomimetic design of CDK inhibitors targeting the recruitment site of the cyclin subunit

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

The role of the phospho-CDK2/cyclin A recruitment site in substrate recognition.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

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https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

REPLACE: a strategy for iterative design of cyclin-binding groove inhibitors.

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7 January 2021

Design, synthesis, biological activity and structural analysis of cyclic peptide inhibitors targeting the substrate recruitment site of cyclin-dependent kinase complexes

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7 January 2021

CDK2/cyclinA inhibitors: targeting the cyclinA recruitment site with small molecules derived from peptide leads

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7 January 2021

Peptide inhibitors of CDK2-cyclin A that target the cyclin recruitment-site: structural variants of the C-terminal Phe.

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7 January 2021

Cellular uptake mechanisms and potential therapeutic utility of peptidic cell delivery vectors: progress 2001-2006.

1 reference

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7 January 2021

Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design

1 reference

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7 January 2021

Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

An Efficient Synthesis of Optically Active α-(t-Butoxycarbonylamino)-aldehydes from α-Amino Acids

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.200900093

7 January 2021

Discovery of a novel family of CDK inhibitors with the program LIDAEUS: structural basis for ligand-induced disordering of the activation loop

1 reference

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7 January 2021