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Principles of CDK regulation
scientific article (publication date: 9 March 1995)
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title
Principles of CDK regulation
(English)
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PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7877684
retrieved
23 April 2017
main subject
cyclin-dependent protein serine/threonine kinase regulator activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0016538
cyclin-dependent protein serine/threonine kinase activity
1 reference
stated in
Gene Ontology release 2020-05-02
Gene Ontology ID
GO:0004693
author name string
Morgan DO
series ordinal
1
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7877684
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23 April 2017
publication date
9 March 1995
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23 April 2017
language of work or name
English
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PubMed
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7877684
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23 April 2017
published in
Nature
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PubMed
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23 April 2017
volume
374
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23 April 2017
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6518
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PubMed
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23 April 2017
page(s)
131-4
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PubMed
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23 April 2017
publication type of scholarly work
review article
1 reference
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Europe PubMed Central
cites work
Animal cell cycles and their control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Control of the yeast cell cycle by the Cdc28 protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of p34 kinases in the G1 to S-phase transition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammalian G1 cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A brain-specific activator of cyclin-dependent kinase 5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle control by a complex of the cyclin HCS26 (PCL1) and the kinase PHO85.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PCL2 (ORFD)-PHO85 cyclin-dependent kinase complex: a cell cycle regulator in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The kin28 protein kinase is associated with a cyclin in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of cyclin-dependent kinase 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase regulation: insights from crystal structure analysis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the domains in cyclin A required for binding to, and activation of, p34cdc2 and p32cdk2 protein kinase subunits
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sequences within the conserved cyclin box of human cyclin A are sufficient for binding to and activation of cdc2 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin is degraded by the ubiquitin pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of E2F transactivation by cyclin/cdk2 complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cdc2 phosphorylation is required for its interaction with cyclin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of phosphorylation by CAK on cyclin binding by CDC2 and CDK2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The cdc2-related protein p40MO15 is the catalytic subunit of a protein kinase that can activate p33cdk2 and p34cdc2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel cyclin associates with MO15/CDK7 to form the CDK-activating kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A cyclin associated with the CDK-activating kinase MO15
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression and activity of p40MO15, the catalytic subunit of cdk-activating kinase, during Xenopus oogenesis and embryogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of p34cdc2 regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclin activation of p34cdc2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cell cycle regulation of the p34cdc2 inhibitory kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of the weel protein kinase by direct action of the nim1/cdr1 mitotic inducer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nim1 kinase promotes mitosis by inactivating Wee1 tyrosine kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct mechanisms for negative regulation of the Wee1 protein kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The decision to enter mitosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAR1 links the signal transduction pathway to the cell cycle machinery in yeast.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct inhibition of the yeast cyclin-dependent kinase Cdc28-Cln by Far1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
P40SDB25, a putative CDK inhibitor, has a role in the M/G1 transition in Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
WAF1, a potential mediator of p53 tumor suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21 is a universal inhibitor of cyclin kinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p21-containing cyclin kinases exist in both active and inactive states
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of FAR1 at the Start of the yeast cell cycle
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human CksHs2 atomic structure: a role for its hexameric assembly in cell cycle control
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Open questions on p16
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Familial melanoma and p16--a hung jury
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2F374131A0
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/374131A0
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7877684
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
618340
Dimensions Publication ID
1029953704
0 references
OpenCitations bibliographic resource ID
618340
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
618340
PubMed publication ID
7877684
2 references
stated in
PubMed
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=7877684
retrieved
23 April 2017
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
618340
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