(Q27657999)

16 November 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor (English)

2 references

PubMed publication ID

19861722

16 November 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

0 references

0 references

Christina Rye Underwood

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Lotte Bjerre Knudsen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Günther H Peters

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

author name string

Patrick Garibay

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Sven Hastrup

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Rainer Rudolph

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

Steffen Reedtz-Runge

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

language of work or name

English

0 references

publication date

27 October 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

11 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

volume

285

1 reference

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11 February 2020

issue

1

1 reference

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11 February 2020

page(s)

723-730

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

Molecular recognition of corticotropin-releasing factor by its G-protein-coupled receptor CRFR1

11 February 2020

cites work

1 reference

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Molecular recognition of parathyroid hormone by its G protein-coupled receptor

20 March 2017

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Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain

20 March 2017

1 reference

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Crystal structure of the incretin-bound extracellular domain of a G protein-coupled receptor

20 March 2017

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Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS

20 March 2017

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Designing a 20-residue protein

20 March 2017

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Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states

20 March 2017

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Conformation of a peptide ligand bound to its G-protein coupled receptor

20 March 2017

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A role for glucagon-like peptide-1 in the central regulation of feeding

20 March 2017

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Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor

20 March 2017

1 reference

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Conformation of glucagon in a lipid-water interphase by 1H nuclear magnetic resonance

20 March 2017

1 reference

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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

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Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain

20 March 2017

1 reference

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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

20 March 2017

1 reference

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Passing the baton in class B GPCRs: peptide hormone activation via helix induction?

20 March 2017

1 reference

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Structural basis of natural ligand binding and activation of the Class II G-protein-coupled secretin receptor

29 September 2017

1 reference

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International Union of Pharmacology. XLVI. G protein-coupled receptor list.

29 September 2017

1 reference

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Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804221

NMR structure and peptide hormone binding site of the first extracellular domain of a type B1 G protein-coupled receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804221

Met-204 and Tyr-205 are together important for binding GLP-1 receptor agonists but not their N-terminally truncated analogues

29 September 2017

1 reference

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A model for receptor-peptide binding at the glucagon-like peptide-1 (GLP-1) receptor through the analysis of truncated ligands and receptors.

29 September 2017

1 reference

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Different domains of the glucagon and glucagon-like peptide-1 receptors provide the critical determinants of ligand selectivity

29 September 2017

1 reference

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The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1.

29 September 2017

1 reference

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The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge

29 September 2017

1 reference

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Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans

29 September 2017

1 reference

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The amino terminal domain of the glucagon-like peptide-1 receptor is a critical determinant of subtype specificity.

29 September 2017

1 reference

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Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas

29 September 2017

1 reference

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Exendin-4 is a high potency agonist and truncated exendin-(9-39)-amide an antagonist at the glucagon-like peptide 1-(7-36)-amide receptor of insulin-secreting beta-cells.

29 September 2017

1 reference

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Structure-activity studies of glucagon-like peptide-1.

2 June 2018

1 reference

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Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.

2 June 2018

1 reference

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Molecular modeling of the three-dimensional structure of GLP-1R and its interactions with several agonists

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

The positive charge at Lys-288 of the glucagon-like peptide-1 (GLP-1) receptor is important for binding the N-terminus of peptide agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

Search for alpha-helical propensity in the receptor-bound conformation of glucagon-like peptide-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

Biological activities of glucagon-like peptide-1 analogues in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.033829

Receptors for glucagon-like peptide-1(7-36) amide on rat insulinoma-derived cells

21 January 2018

1 reference

12 December 2020

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

1 reference

12 December 2020

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

1 reference

12 December 2020

Structure of glucagon-like peptide (7-36) amide in a dodecylphosphocholine micelle as determined by 2D NMR

1 reference

12 December 2020

High potency antagonists of the pancreatic glucagon-like peptide-1 receptor

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.033829

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19861722%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

19861722

2 references