(Q27659023)

9

0 references

Gaya K. Amarasinghe

Gaya K Amarasinghe

12

0 references

Dominika Borek

Dominika M Borek

3

0 references

Christopher F Basler

Christopher F Basler

11

0 references

Parameshwaran Ramanan

6

Parameshwaran Ramanan

0 references

Daisy W Leung

1

Daisy W Leung

0 references

Kathleen C Prins

2

Kathleen C Prins

0 references

Mina Farahbakhsh

4

Mina Farahbakhsh

0 references

Jay Nix

7

Jay C Nix

0 references

Luke A Helgeson

8

Luke A Helgeson

0 references

Richard B Honzatko

10

Richard B Honzatko

0 references

author name string

JoAnn M Tufariello

Nature Structural & Molecular Biology

5

0 references

publication date

February 2010

0 references

published in

0 references

volume

17

0 references

issue

2

0 references

page(s)

165-72

0 references

cites work

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5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

20 March 2017

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Structural basis of double-stranded RNA recognition by the RIG-I like receptor MDA5

20 March 2017

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Solution structures of cytosolic RNA sensor MDA5 and LGP2 C-terminal domains: identification of the RNA recognition loop in RIG-I-like receptors

20 March 2017

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The RIG-I-like receptor LGP2 recognizes the termini of double-stranded RNA

20 March 2017

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The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA

20 March 2017

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Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1

20 March 2017

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Structure of the Ebola VP35 interferon inhibitory domain

20 March 2017

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Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction

20 March 2017

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Structure and function of LGP2, a DEX(D/H) helicase that regulates the innate immunity response

20 March 2017

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MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

20 March 2017

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

20 March 2017

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Optimal description of a protein structure in terms of multiple groups undergoing TLS motion

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Using NMRView to visualize and analyze the NMR spectra of macromolecules

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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wARP: improvement and extension of crystallographic phases by weighted averaging of multiple-refined dummy atomic models

20 March 2017

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Automated refinement of protein models

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

20 March 2017

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Pushing the boundaries of molecular replacement with maximum likelihood

20 March 2017

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The finer things in X-ray diffraction data collection

20 March 2017

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20 March 2017

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

22 April 2017

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Shape complementarity at protein/protein interfaces

20 March 2017

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The interpretation of protein structures: Estimation of static accessibility

20 March 2017

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Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery

20 March 2017

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MOLREP: an Automated Program for Molecular Replacement

22 April 2017

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Evasion of interferon responses by Ebola and Marburg viruses

22 April 2017

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RIG-I activation inhibits ebolavirus replication

29 September 2017

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Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain

29 September 2017

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Expression, purification, crystallization and preliminary X-ray studies of the Ebola VP35 interferon inhibitory domain.

29 September 2017

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Approaching the RNA ligand for RIG-I?

29 September 2017

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RIG-I and dsRNA-induced IFNbeta activation

29 September 2017

1 reference

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Differential recognition of double-stranded RNA by RIG-I-like receptors in antiviral immunity.

29 September 2017

1 reference

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A filovirus-unique region of Ebola virus nucleoprotein confers aberrant migration and mediates its incorporation into virions

29 September 2017

1 reference

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Whole-genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein

29 September 2017

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Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

5'-triphosphate-dependent activation of PKR by RNAs with short stem-loops

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

The Ebola virus VP35 protein is a suppressor of RNA silencing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Role of RIG-I, MDA-5, and PKR on the expression of inflammatory chemokines induced by synthetic dsRNA in airway epithelial cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Principles of intracellular viral recognition.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replication

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola virus VP35-VP40 interaction is sufficient for packaging 3E-5E minigenome RNA into virus-like particles.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Global suppression of the host antiviral response by Ebola- and Marburgviruses: increased antagonism of the type I interferon response is associated with enhanced virulence

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Homo-oligomerization facilitates the interferon-antagonist activity of the ebolavirus VP35 protein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola virus: the role of macrophages and dendritic cells in the pathogenesis of Ebola hemorrhagic fever

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

A C-terminal basic amino acid motif of Zaire ebolavirus VP35 is essential for type I interferon antagonism and displays high identity with the RNA-binding domain of another interferon antagonist, the NS1 protein of influenza A virus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola virus ecology: a continuing mystery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Ebola virus VP40 drives the formation of virus-like filamentous particles along with GP

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

The Ebola virus VP35 protein functions as a type I IFN antagonist.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Purification and characterization of transcribed RNAs using gel filtration chromatography.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2872155

Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients

2 June 2018

1 reference

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference