(Q27660584)

22 June 2017

title

Structural determinants of cadherin-23 function in hearing and deafness (English)

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22 June 2017

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3

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22 June 2017

Marcos Sotomayor

1

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David P. Corey

object named as

David P Corey

series ordinal

4

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author name string

Wilhelm A Weihofen

series ordinal

2

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22 June 2017

language of work or name

English

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publication date

1 April 2010

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22 June 2017

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22 June 2017

volume

66

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22 June 2017

issue

1

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22 June 2017

page(s)

85-100

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describes a project that uses

22 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2948466/fullTextXML

inferred from PubMed Central ID database lookup

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Survey of the frequency of USH1 gene mutations in a cohort of Usher patients shows the importance of cadherin 23 and protocadherin 15 genes and establishes a detection rate of above 90%

20 March 2017

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Mutation of CDH23, encoding a new member of the cadherin gene family, causes Usher syndrome type 1D

20 March 2017

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Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of the novel cadherin-like gene CDH23

20 March 2017

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A photoreceptor-specific cadherin is essential for the structural integrity of the outer segment and for photoreceptor survival

20 March 2017

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The mouse Ames waltzer hearing-loss mutant is caused by mutation of Pcdh15, a novel protocadherin gene

20 March 2017

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29 September 2017

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A mouse model for nonsyndromic deafness (DFNB12) links hearing loss to defects in tip links of mechanosensory hair cells

29 September 2017

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29 September 2017

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Gene structure and mutant alleles of PCDH15: nonsyndromic deafness DFNB23 and type 1 Usher syndrome

29 September 2017

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29 September 2017

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29 September 2017

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Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells

29 September 2017

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29 September 2017

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The micromachinery of mechanotransduction in hair cells

29 September 2017

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Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels

29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Mechanism and dynamics of cadherin adhesion

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Type II cadherin ectodomain structures: implications for classical cadherin specificity.

29 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Ca2+ changes the force sensitivity of the hair-cell transduction channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Cadherin mechanics and complexation: the importance of calcium binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Specificity of cell-cell adhesion by classical cadherins: Critical role for low-affinity dimerization through beta-strand swapping

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Characterization of Usher syndrome type I gene mutations in an Usher syndrome patient population

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Cadherin 23 is a component of the tip link in hair-cell stereocilia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Cadherin-mediated cell-cell adhesion: sticking together as a family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Mutations in the calcium-binding motifs of CDH23 and the 35delG mutation in GJB2 cause hearing loss in one family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

CDH23 mutation and phenotype heterogeneity: a profile of 107 diverse families with Usher syndrome and nonsyndromic deafness.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Steered molecular dynamics and mechanical functions of proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

High-resolution structure of hair-cell tip links

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Cadherin interaction probed by atomic force microscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Molecular dynamics study of unbinding of the avidin-biotin complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Dynamic strength of molecular adhesion bonds

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Calcium imaging of single stereocilia in hair cells: localization of transduction channels at both ends of tip links

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Molecular dynamics simulations in biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Tip-link integrity and mechanical transduction in vertebrate hair cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Very low calcium content of cochlear endolymph, an extracellular fluid

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Kinetics of the receptor current in bullfrog saccular hair cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Cross-links between stereocilia in the guinea pig organ of Corti, and their possible relation to sensory transduction

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Calcium gradients in inner ear endolymph

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

Compliance of the hair bundle associated with gating of mechanoelectrical transduction channels in the bullfrog's saccular hair cell

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2948466

UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes

2 June 2018

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Modulation of E-cadherin monomer folding by cooperative binding of calcium ions

27 November 2018

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Distribution and frequencies of CDH23 mutations in Japanese patients with non-syndromic hearing loss.

27 November 2018

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Calcium-dependent stability studies of domains 1 and 2 of epithelial cadherin

27 November 2018

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Force probe molecular dynamics simulations.

27 November 2018

1 reference

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A dissection of specific and non-specific protein-protein interfaces

27 November 2018

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Mutations in cadherin 23 affect tip links in zebrafish sensory hair cells

27 November 2018

1 reference

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Measurement of Ca2+-Binding Constants of Proteins and Presentation of the CaLigator Software

27 November 2018

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Genomic structure, alternative splice forms and normal and mutant alleles of cadherin 23 (Cdh23).

27 November 2018

1 reference

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In search of the hair-cell gating spring elastic properties of ankyrin and cadherin repeats

27 November 2018

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12 December 2020

Forced dissociation of the strand dimer interface between C-cadherin ectodomains

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12 December 2020

The tip-link antigen, a protein associated with the transduction complex of sensory hair cells, is protocadherin-15

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12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

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12 December 2020

Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding

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12 December 2020

Plasma membrane Ca2+-ATPase extrudes Ca2+ from hair cell stereocilia

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12 December 2020

10.1016/J.NEURON.2010.03.028

Identifiers

DOI

1 reference

22 June 2017

0 references

1 reference