(Q27662749)

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Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement

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scholarly article

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Complexes of Bacterial Nicotinate Mononucleotide Adenylyltransferase with Inhibitors: Implication for Structure-Based Drug Design and Improvement (English)

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author name string

Nian Huang

1

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Rohit Kolhatkar

2

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Yvonne Eyobo

3

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Leonardo Sorci

4

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Irina Rodionova

5

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Andrei L Osterman

6

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Alexander D Mackerell

7

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Hong Zhang

8

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language of work or name

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publication date

22 July 2010

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Journal of Medicinal Chemistry

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53

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14

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5229-39

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Targeting NAD Biosynthesis in Bacterial Pathogens: Structure-Based Development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadD

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20 March 2017

Structure and Function of an ADP-Ribose-Dependent Transcriptional Regulator of NAD Metabolism

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20 March 2017

Kinetic and X-Ray Structural Evidence for Negative Cooperativity in Substrate Binding to Nicotinate Mononucleotide Adenylyltransferase (NMAT) from Bacillus anthracis

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20 March 2017

Structure of nicotinic acid mononucleotide adenylyltransferase fromBacillus anthracis

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20 March 2017

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20 March 2017

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

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From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways

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20 March 2017

Crystal structures of E. coli nicotinate mononucleotide adenylyltransferase and its complex with deamido-NAD

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20 March 2017

Structure of human nicotinamide/nicotinic acid mononucleotide adenylyltransferase. Basis for the dual substrate specificity and activation of the oncolytic agent tiazofurin

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20 March 2017

Identification, characterization, and crystal structure of Bacillus subtilis nicotinic acid mononucleotide adenylyltransferase

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20 March 2017

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20 March 2017

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20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

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20 March 2017

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A graphical user interface to the CCP4 program suite

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20 March 2017

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Hydrolase regulates NAD+ metabolites and modulates cellular redox

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Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis

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20 March 2017

Identification of the Escherichia coli nicotinic acid mononucleotide adenylyltransferase gene

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20 March 2017

Drugs for bad bugs: confronting the challenges of antibacterial discovery

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Antibiotics for emerging pathogens

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Invasive methicillin-resistant Staphylococcus aureus infections in the United States

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7 April 2017

Recent developments in the PHENIX software for automated crystallographic structure determination

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New strategies for combating multidrug-resistant bacteria

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29 September 2017

Structure and function of nicotinamide mononucleotide adenylyltransferase.

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29 September 2017

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The biosynthesis of nicotinamide adenine dinucleotides in bacteria

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Identifiers

10.1021/JM100377F

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