(Q34453460)

2 August 2017

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title

Exploiting genomics to discover new antibiotics (English)

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2 August 2017

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McDevitt D

1

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2 August 2017

Rosenberg M

series ordinal

2

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2 August 2017

publication date

1 December 2001

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2 August 2017

published in

Trends in Microbiology

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2 August 2017

volume

9

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2 August 2017

issue

12

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2 August 2017

page(s)

611-617

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Epidemiologic trends in nosocomial and community-acquired infections due to antibiotic-resistant gram-positive bacteria: the role of streptogramins and other newer compounds.

2 August 2017

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Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin

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7 January 2021

The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria

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7 January 2021

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd

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7 January 2021

Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

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7 January 2021

Evolution of two-component signal transduction

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7 January 2021

MurA (MurZ), the enzyme that catalyzes the first committed step in peptidoglycan biosynthesis, is essential in Escherichia coli

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7 January 2021

Two active forms of UDP-N-acetylglucosamine enolpyruvyl transferase in gram-positive bacteria

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7 January 2021

Initial sequencing and analysis of the human genome

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7 January 2021

The Sequence of the Human Genome

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7 January 2021

Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis

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7 January 2021

Rapid method for the identification of essential genes in Staphylococcus aureus

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7 January 2021

A genomic analysis of two-component signal transduction in Streptococcus pneumoniae

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A genome-based approach for the identification of essential bacterial genes.

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7 January 2021

Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoter

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7 January 2021

Use of the lactococcal nisA promoter to regulate gene expression in gram-positive bacteria: comparison of induction level and promoter strength.

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7 January 2021

Integrational plasmids for the tetracycline-regulated expression of genes in Streptococcus pneumoniae

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7 January 2021

The essential two-component regulatory system encoded by yycF and yycG modulates expression of the ftsAZ operon in Bacillus subtilis

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7 January 2021

Regulated gene expression in Staphylococcus aureus for identifying conditional lethal phenotypes and antibiotic mode of action

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Regulated ectopic expression and allelic-replacement mutagenesis as a method for gene essentiality testing in Staphylococcus aureus

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7 January 2021

Selection of bacterial virulence genes that are specifically induced in host tissues.

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7 January 2021

In vivo genetic analysis of bacterial virulence

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7 January 2021

Fluorescence-based isolation of bacterial genes expressed within host cells

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7 January 2021

Simultaneous identification of bacterial virulence genes by negative selection.

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7 January 2021

Bacterial virulence as a target for antimicrobial chemotherapy

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7 January 2021

DNA arrays for analysis of gene expression

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7 January 2021

Bacterial transcript imaging by hybridization of total RNA to oligonucleotide arrays

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7 January 2021

The importance of genome analysis to the drug discovery process

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7 January 2021

Identification and analysis of bacterial protein secretion inhibitors utilizing a SecA-LacZ reporter fusion system

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7 January 2021

Antibacterial agents that inhibit two-component signal transduction systems

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7 January 2021

Drug target validation: lethal infection blocked by inducible peptide

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7 January 2021

Inhibitors of aminoacyl-tRNA synthetases as novel anti-infectives

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7 January 2021

Rational design of femtomolar inhibitors of isoleucyl tRNA synthetase from a binding model for pseudomonic acid-A

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7 January 2021

A potent seryl tRNA synthetase inhibitor SB-217452 isolated from a Streptomyces species

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7 January 2021

Processing of the N termini of nascent polypeptide chains requires deformylation prior to methionine removal

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7 January 2021

Crystal structure of the Escherichia coli peptide deformylase

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7 January 2021

Structure of peptide deformylase and identification of the substrate binding site

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7 January 2021

Actinonin, a naturally occurring antibacterial agent, is a potent deformylase inhibitor

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7 January 2021

Hydroxamic acid derivatives as potent peptide deformylase inhibitors and antibacterial agents

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7 January 2021

Antibiotic Activity and Characterization of BB-3497, a Novel Peptide Deformylase Inhibitor

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7 January 2021

Peptide deformylase as an antibacterial drug target: target validation and resistance development

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7 January 2021

Peptide deformylase in Staphylococcus aureus: resistance to inhibition is mediated by mutations in the formyltransferase gene

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7 January 2021

Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities

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7 January 2021

Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery

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7 January 2021

Molecular basis for triclosan activity involves a flipping loop in the active site

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7 January 2021

Structure of the complex between the antibiotic cerulenin and its target, beta-ketoacyl-acyl carrier protein synthase

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7 January 2021

Refined structures of beta-ketoacyl-acyl carrier protein synthase III

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7 January 2021

10.1016/S0966-842X(01)02235-1

Identifiers

DOI

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release_6rcqtdxtajestdi6dlzogwgmzi

2 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/6rcqtdxtajestdi6dlzogwgmzi

24 November 2022

mapped directly with Wikidata item

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