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An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase
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title
An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase
(English)
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main subject
bioengineering
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biotechnology
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microbiology
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allosteric inhibitor
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based on heuristic
inferred from title
author
Frank Sicheri
series ordinal
6
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author name string
Stephen Orlicky
series ordinal
1
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Xiaojing Tang
series ordinal
2
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Victor Neduva
series ordinal
3
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Nadine Elowe
series ordinal
4
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Eric D Brown
series ordinal
5
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Mike Tyers
series ordinal
7
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publication date
July 2010
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published in
Nature Biotechnology
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volume
28
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issue
7
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page(s)
733-7
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cites work
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: tipping the scales of cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Ancestral paralogs and pseudoparalogs and their role in the emergence of the eukaryotic cell
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Phosducin induces a structural change in transducin beta gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Prolyl oligopeptidase: an unusual beta-propeller domain regulates proteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
TOR signaling in growth and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
The ubiquitin system
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Cdc53 is a scaffold protein for multiple Cdc34/Skp1/F-box proteincomplexes that regulate cell division and methionine biosynthesis in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Function and regulation of cullin-RING ubiquitin ligases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
The WD repeat: a common architecture for diverse functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
20 March 2017
Structural diversity of G protein-coupled receptors and significance for drug discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
7 April 2017
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
7 April 2017
A hitchhiker's guide to the cullin ubiquitin ligases: SCF and its kin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
7 April 2017
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
7 April 2017
Phosphorylation of Sic1p by G1 Cdk required for its degradation and entry into S phase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
7 April 2017
Identification of SCF ubiquitin ligase substrates by global protein stability profiling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
Drug discovery in the ubiquitin-proteasome system.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
BINOL: a versatile chiral reagent
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
Inducible dissociation of SCF(Met30) ubiquitin ligase mediates a rapid transcriptional response to cadmium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
Inactivation of hCDC4 can cause chromosomal instability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
Beta propellers: structural rigidity and functional diversity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
29 September 2017
Allosteric Modulation of G Protein–Coupled Receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
27 November 2018
Unclosed beta-propellers display stable structures: implications for substrate access to the active site of prolyl oligopeptidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
27 November 2018
High-throughput screening identifies inhibitors of the SARS coronavirus main proteinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4445864
retrieved
27 November 2018
Prolyl Oligopeptidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Processing of X-ray diffraction data collected in oscillation mode
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Improved methods for building protein models in electron density maps and the location of errors in these models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystallographic refinement of ligand complexes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Refinement of macromolecular structures by the maximum-likelihood method
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Saccharomyces Genome Database (SGD) provides tools to identify and analyze sequences from Saccharomyces cerevisiae and related sequences from other organisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
InterProScan--an integration platform for the signature-recognition methods in InterPro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Universal Protein Resource (UniProt) in 2010
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Maximum discrimination hidden Markov models of sequence consensus
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
ProbCons: Probabilistic consistency-based multiple sequence alignment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FNBT.1646
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/NBT.1646
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Dimensions Publication ID
1037502423
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Fatcat ID
release_jsbtk2h2cneedppaslrzaftatu
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PMC publication ID
4445864
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PubMed publication ID
20581844
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ResearchGate publication ID
44803610
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