(Q27663271)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Structure of a thyroid hormone receptor DNA-binding domain homodimer bound to an inverted palindrome DNA response element (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

author name string

Yi Chen

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

publication date

7 July 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

published in

Molecular Endocrinology

1 reference

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7 February 2020

volume

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

page(s)

1650-1664

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

7 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5417456/fullTextXML

inferred from PubMed Central ID database lookup

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A method for efficient production of recombinant thyroid hormone receptors reveals that receptor homodimer-DNA binding is enhanced by the coactivator TIF2

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Monomeric complex of human orphan estrogen related receptor-2 with DNA: a pseudo-dimer interface mediates extended half-site recognition

26 May 2017

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Structural basis of VDR-DNA interactions on direct repeat response elements

26 May 2017

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Combinatorial control of gene expression by nuclear receptors and coregulators

26 May 2017

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Physiological and molecular basis of thyroid hormone action

26 May 2017

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Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1

26 May 2017

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Structural basis of RXR-DNA interactions

26 May 2017

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Structural elements of an orphan nuclear receptor-DNA complex

26 May 2017

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Transcriptional activation and repression by RORalpha, an orphan nuclear receptor required for cerebellar development

26 May 2017

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The RXR heterodimers and orphan receptors

26 May 2017

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The nuclear receptor superfamily: the second decade

26 May 2017

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The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements

26 May 2017

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Molecular mechanisms of action of steroid/thyroid receptor superfamily members

26 May 2017

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Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha

26 May 2017

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Structural determinants of nuclear receptor assembly on DNA direct repeats

26 May 2017

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Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

26 May 2017

1 reference

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A robust bulk-solvent correction and anisotropic scaling procedure

26 May 2017

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Processing of X-ray diffraction data collected in oscillation mode

26 May 2017

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Quantification of ligand-regulated nuclear receptor corepressor and coactivator binding, key interactions determining ligand potency and efficacy for the thyroid hormone receptor

29 September 2017

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Nuclear receptors: decoding metabolic disease

29 September 2017

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Nuclear receptor structure: implications for function

29 September 2017

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Mechanism of the nuclear receptor molecular switch

29 September 2017

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Nuclear export: DNA-binding domains find a surprising partner

29 September 2017

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Nuclear-receptor interactions on DNA-response elements

29 September 2017

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NMR spectroscopic studies of the DNA-binding domain of the monomer-binding nuclear orphan receptor, human estrogen related receptor-2. The carboxyl-terminal extension to the zinc-finger region is unstructured in the free form of the protein.

29 September 2017

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Structure of the retinoid X receptor alpha DNA binding domain: a helix required for homodimeric DNA binding

29 September 2017

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The patterns of binding of RAR, RXR and TR homo- and heterodimers to direct repeats are dictated by the binding specificites of the DNA binding domains.

29 September 2017

1 reference

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The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Determinants of target gene specificity for ROR alpha 1: monomeric DNA binding by an orphan nuclear receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Structural determinants of DNA-binding specificity by steroid receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Differential DNA binding by monomeric, homodimeric, and potentially heteromeric forms of the thyroid hormone receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Oligomeric binding of T3 receptor is required for maximal T3 response.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Capacity for cooperative binding of thyroid hormone (T3) receptor dimers defines wild type T3 response elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Participation of non-zinc finger residues in DNA binding by two nuclear orphan receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Recognition by the thyroid hormone receptor of canonical DNA response elements

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Determinants for selective RAR and TR recognition of direct repeat HREs.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Dimerization interfaces of thyroid hormone, retinoic acid, vitamin D, and retinoid X receptors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Thyroid hormone receptor binds with unique properties to response elements that contain hexamer domains in an inverted palindrome arrangement.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Thyroid hormone alters in vitro DNA binding of monomers and dimers of thyroid hormone receptors

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Human thyroid receptor forms tetramers in solution, which dissociate into dimers upon ligand binding.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Structural analysis of RXR-VDR interactions on DR3 DNA.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

On the possibility of the observation of valence electron density for individual bonds in proteins in conventional difference maps

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Mechanisms of thyroid hormone action: insights from X-ray crystallographic and functional studies.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Delineation of three different thyroid hormone-response elements in promoter of rat sarcoplasmic reticulum Ca2+ATPase gene. Demonstration that retinoid X receptor binds 5' to thyroid hormone receptor in response element 1.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5417456

Thyroid hormone response element organization dictates the composition of active receptor

27 November 2018

1 reference

12 December 2020

Function of nuclear co-repressor protein on thyroid hormone response elements is regulated by the receptor A/B domain

1 reference

12 December 2020

An everted repeat mediates retinoic acid induction of the gamma F-crystallin gene: evidence of a direct role for retinoids in lens development

1 reference

12 December 2020

Two nuclear signalling pathways for vitamin D

1 reference

12 December 2020

Low-resolution structures of thyroid hormone receptor dimers and tetramers in solution

1 reference

12 December 2020

Stoichiometric and steric principles governing repression by nuclear hormone receptors

1 reference

12 December 2020

Thyroid hormone receptor homodimers can function as ligand-sensitive repressors

1 reference

12 December 2020

1 reference

12 December 2020

A canonical structure for the ligand-binding domain of nuclear receptors

1 reference

12 December 2020

Different dimerization activities of alpha and beta thyroid hormone receptor isoforms

1 reference

12 December 2020

Identifiers

DOI

10.1210/ME.2010-0129

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20610536%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

20610536

1 reference