(Q27665220)

English

Structures of the Michaelis Complex (1.2 Å) and the Covalent Acyl Intermediate (2.0 Å) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis β-Lactamase K73A and E166A Mutants,

scientific article published on October 25, 2010

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Structures of the Michaelis Complex (1.2 Å) and the Covalent Acyl Intermediate (2.0 Å) of Cefamandole Bound in the Active Sites of the Mycobacterium tuberculosis β-Lactamase K73A and E166A Mutants, (English)

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Structures of the Michaelis complex (1.2 Å) and the covalent acyl intermediate (2.0 Å) of cefamandole bound in the active sites of the Mycobacterium tuberculosis β-lactamase K73A and E166A mutants (English)

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

Mycobacterium tuberculosis

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John S Blanchard

3

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John S Blanchard

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author name string

Hua Xu

2

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Lee W. Tremblay

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

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16 November 2010

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25 October 2010

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

full work available at URL

https://europepmc.org/articles/pmc2981129?pdf=render

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20961112/pdf/?tool=EBI

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20961112/?tool=EBI

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1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://europepmc.org/articles/PMC2981129

online access status

content deliverer

Europe PubMed Central

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://europepmc.org/articles/PMC2981129?pdf=render

Portable Document Format

online access status

content deliverer

Europe PubMed Central

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://doi.org/10.1021/bi1015088

online access status

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20961112

6 August 2024

https://pubs.acs.org/doi/pdf/10.1021/bi1015088

1 reference

10.1021/BI1015088

https://api.crossref.org/works/10.1021/BI1015088

6 August 2024

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49

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45

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9685-7

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Biochemical and Structural Characterization of Mycobacterium tuberculosis β-Lactamase with the Carbapenems Ertapenem and Doripenem

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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20 March 2017

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1 reference

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20 March 2017

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1 reference

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29 September 2017

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1 reference

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29 September 2017

Beta-lactamases: a survey of protein diversity

1 reference

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Mycobacterial cell wall: structure and role in natural resistance to antibiotics

1 reference

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29 September 2017

The structure of β-lactamases

1 reference

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Irreversible inhibition of the Mycobacterium tuberculosis beta-lactamase by clavulanate

1 reference

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2 June 2018

Carbapenems and SHV-1 beta-lactamase form different acyl-enzyme populations in crystals and solution

1 reference

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Molecular mechanisms of antibiotic resistance: QM/MM modelling of deacylation in a class A beta-lactamase

1 reference

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27 November 2018

Ab initio QM/MM study of class A beta-lactamase acylation: dual participation of Glu166 and Lys73 in a concerted base promotion of Ser70.

1 reference

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An Enzyme from Bacteria able to Destroy Penicillin

13

1 reference

10.1021/BI1015088

https://api.crossref.org/works/10.1021/BI1015088

6 August 2024

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10.1021/BI1015088

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release_2pomlfr6rzbcphkhmzepyc3rya

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