(Q27666524)

GOA release 2020-03-11

author

Osamu Nureki

10

0 references

Naoshi Dohmae

5

0 references

Ryuichiro Ishitani

7

0 references

Junken Aoki

object named as

Junken Aoki

9

0 references

Emiko Mihara

4

object named as

Emiko Mihara

0 references

Junichi Takagi

8

object named as

Junichi Takagi

0 references

author name string

Hiroshi Nishimasu

1

0 references

Shinichi Okudaira

2

0 references

Kotaro Hama

3

0 references

Asuka Inoue

Nature Structural & Molecular Biology

6

0 references

language of work or name

English

0 references

publication date

February 2011

0 references

published in

0 references

volume

18

0 references

issue

2

0 references

page(s)

205-12

0 references

cites work

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

1 reference

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

31 March 2020

1 reference

Lysophosphatidic acid (LPA) and its receptors

31 March 2020

1 reference

The ins and outs of lysophosphatidic acid signaling.

31 March 2020

1 reference

Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior

31 March 2020

1 reference

Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid.

31 March 2020

1 reference

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

31 March 2020

1 reference

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs

31 March 2020

1 reference

Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling

31 March 2020

1 reference

Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases

31 March 2020

1 reference

Expression of autotaxin (NPP-2) is closely linked to invasiveness of breast cancer cells

31 March 2020

1 reference

Identification of human renal cell carcinoma associated genes by suppression subtractive hybridization

31 March 2020

1 reference

Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells

31 March 2020

1 reference

Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma.

31 March 2020

1 reference

Autotaxin is overexpressed in glioblastoma multiforme and contributes to cell motility of glioblastoma by converting lysophosphatidylcholine to lysophosphatidic acid

31 March 2020

1 reference

Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA1.

31 March 2020

1 reference

Autotaxin inhibition: challenges and progress toward novel anti-cancer agents

31 March 2020

1 reference

NPP-type ectophosphodiesterases: unity in diversity

31 March 2020

1 reference

Substrate-specifying determinants of the nucleotide pyrophosphatases/phosphodiesterases NPP1 and NPP2.

31 March 2020

1 reference

A rapid screening method for cell lines producing singly-tagged recombinant proteins using the "TARGET tag" system

31 March 2020

1 reference

Proteolytic maturation and activation of autotaxin (NPP2), a secreted metastasis-enhancing lysophospholipase D

31 March 2020

1 reference

How vitronectin binds PAI-1 to modulate fibrinolysis and cell migration

31 March 2020

1 reference

Structural and functional analysis of the plasminogen activator inhibitor-1 binding motif in the somatomedin B domain of vitronectin

31 March 2020

1 reference

Regulation and biological activities of the autotaxin-LPA axis.

31 March 2020

1 reference

Stimulation of tumor cell motility linked to phosphodiesterase catalytic site of autotaxin

31 March 2020

1 reference

The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site

31 March 2020

1 reference

Structural and catalytic similarities between nucleotide pyrophosphatases/phosphodiesterases and alkaline phosphatases

31 March 2020

1 reference

Structural and functional comparisons of nucleotide pyrophosphatase/phosphodiesterase and alkaline phosphatase: implications for mechanism and evolution

31 March 2020

1 reference

Phosphodiesterase-Ialpha/autotaxin's MORFO domain regulates oligodendroglial process network formation and focal adhesion organization

31 March 2020

1 reference

Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena.

31 March 2020

1 reference

An essential oligomannosidic glycan chain in the catalytic domain of autotaxin, a secreted lysophospholipase-D

31 March 2020

1 reference

Domain interplay mediated by an essential disulfide linkage is critical for the activity and secretion of the metastasis-promoting enzyme autotaxin

31 March 2020

1 reference

Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family

31 March 2020

1 reference

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate

31 March 2020

1 reference

Structure of human pancreatic lipase

31 March 2020

1 reference

31 March 2020

A short history of SHELX

1 reference

The CCP4 suite: programs for protein crystallography

31 March 2020

1 reference

Automated MAD and MIR structure solution

31 March 2020

1 reference

Coot: model-building tools for molecular graphics

31 March 2020

1 reference

PHENIX: building new software for automated crystallographic structure determination

31 March 2020

1 reference

Molecular replacement with MOLREP

31 March 2020

1 reference

Searching protein structure databases with DaliLite v.3

31 March 2020

1 reference

Cyclic phosphatidic acid is produced by autotaxin in blood

31 March 2020

1 reference

Expression of autotaxin mRNA in human hepatocellular carcinoma

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21240269

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21240269

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21240269