(Q27667378)

21 June 2017

title

Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement (English)

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21 June 2017

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4

Lukasz Lebioda

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21 June 2017

Leslie L Lovelace

1

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21 June 2017

Christopher L Cooper

series ordinal

2

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21 June 2017

James M Sodetz

series ordinal

3

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21 June 2017

language of work or name

English

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publication date

25 March 2011

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Journal of Biological Chemistry

21 June 2017

published in

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21 June 2017

volume

286

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21 June 2017

issue

20

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21 June 2017

page(s)

17585-17592

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The structural basis for membrane binding and pore formation by lymphocyte perforin

21 June 2017

cites work

1 reference

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Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron

20 March 2017

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Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

20 March 2017

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A common fold mediates vertebrate defense and bacterial attack

20 March 2017

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Cholesterol-dependent cytolysins, a family of versatile pore-forming toxins

20 March 2017

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Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential

20 March 2017

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Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site

20 March 2017

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Crystal structure of human epidermal growth factor and its dimerization

20 March 2017

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20 March 2017

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20 March 2017

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20 March 2017

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Inference of macromolecular assemblies from crystalline state

21 January 2018

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20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

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The CCP4 suite: programs for protein crystallography

20 March 2017

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

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The human complement regulatory protein CD59 binds to the alpha-chain of C8 and to the "b"domain of C9

20 March 2017

1 reference

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Defining the CD59-C9 binding interaction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Structural basis of pore formation by the bacterial toxin pneumolysin

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The hexopyranosyl residue that is C-glycosidically linked to the side chain of tryptophan-7 in human RNase Us is alpha-mannopyranose

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Molecular organization and function of the complement system

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

A deliberate approach to screening for initial crystallization conditions of biological macromolecules

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Molecular characterization of the alpha subunit of complement component C8 (GcC8alpha) in the nurse shark (Ginglymostoma cirratum)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Incorporation of human complement C8 into the membrane attack complex is mediated by a binding site located within the C8beta MACPF domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The evolution and structural anatomy of the small molecule metabolic pathways in Escherichia coli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The lipocalin protein family: structural and sequence overview

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The membrane attack complex of complement. Assembly, structure and cytotoxic activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Identity of the segment of human complement C8 recognized by complement regulatory protein CD59.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

A central role of perforin in cytolysis?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Expression and characterization of recombinant subunits of human complement component C8: further analysis of the function of C8 alpha and C8 gamma.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Evidence of direct insertion of terminal complement proteins into cell membrane bilayers during cytolysis. Labeling by a photosensitive membrane probe reveals a major role for the eighth and ninth components

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

The relationship between polymerization of complement component C9 and membrane channel formation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Comparison of channels formed by poly C9, C5b-8 and the membrane attack complex of complement

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

Chlamydial homologues of the MACPF (MAC/perforin) domain

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

A solution for the best rotation to relate two sets of vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

Complement components C5 and C7: recombinant factor I modules of C7 bind to the C345C domain of C5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

The architectural transition of human complement component C9 to poly(C9).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

On the Evolution of Biochemical Syntheses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

Functional Studies of the MACPF Domain of Human Complement Protein C8α Reveal Sites for Simultaneous Binding of C8β, C8γ, and C9†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

Crystal structure of enolase indicates that enolase and pyruvate kinase evolved from a common ancestor

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3093833

27 November 2018

https://api.crossref.org/works/10.1074%2FJBC.M111.219766

An indel within the C8 alpha subunit of human complement C8 mediates intracellular binding of C8 gamma and formation of C8 alpha-gamma

21 January 2018

1 reference

12 December 2020

Solution structures of the first and fourth TSR domains of F-spondin

1 reference

12 December 2020

Functional domains of the alpha subunit of the eighth component of human complement: identification and characterization of a distinct binding site for the gamma chain

1 reference

12 December 2020

The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure

1 reference

12 December 2020

Identification of disulfide bonds in the ninth component (C9) of human complement

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.219766

1 reference

release_u6bjyn6hvzfrnoiukqorcxl2la

21 June 2017

Fatcat ID

0 references

PMC publication ID

3093833

0 references

1 reference