(Q27667904)

2

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Christian Schoenau

3

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Jochen Huber

4

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John J G Tesmer

Molecular basis for activation of G protein-coupled receptor kinases

5

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publication date

August 2011

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published in

Molecular Pharmacology

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volume

80

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issue

2

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page(s)

294-303

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cites work

1 reference

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Structure of Human G Protein-Coupled Receptor Kinase 2 in Complex with the Kinase Inhibitor Balanol

20 March 2017

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Structures of rhodopsin kinase in different ligand states reveal key elements involved in G protein-coupled receptor kinase activation

20 March 2017

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Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbetagamma

20 March 2017

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The protein kinase complement of the human genome

20 March 2017

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Structural mechanism for STI-571 inhibition of abelson tyrosine kinase

20 March 2017

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Crystal structure of the potent natural product inhibitor balanol in complex with the catalytic subunit of cAMP-dependent protein kinase

20 March 2017

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Expression, purification, and characterization of the G protein-coupled receptor kinase GRK5

20 March 2017

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Coot: model-building tools for molecular graphics

20 March 2017

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

20 March 2017

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Use of TLS parameters to model anisotropic displacements in macromolecular refinement

20 March 2017

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20 March 2017

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Expression and characterization of two beta-adrenergic receptor kinase isoforms using the baculovirus expression system

29 September 2017

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Purification and characterization of rhodopsin kinase

20 March 2017

1 reference

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Proteus in the world of proteins: conformational changes in protein kinases.

20 March 2017

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Through the "gatekeeper door": exploiting the active kinase conformation

29 September 2017

1 reference

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Improving physical realism, stereochemistry, and side-chain accuracy in homology modeling: Four approaches that performed well in CASP8.

29 September 2017

1 reference

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A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases

29 September 2017

1 reference

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Protein kinase inhibitors: contributions from structure to clinical compounds

29 September 2017

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GRK mythology: G-protein receptor kinases in cardiovascular disease

29 September 2017

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EGFR tyrosine kinase inhibitors in lung cancer: an evolving story

29 September 2017

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A new paradigm for protein kinase inhibition: blocking phosphorylation without directly targeting ATP binding

29 September 2017

1 reference

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Enhancing recombinant protein quality and yield by protein stability profiling

29 September 2017

1 reference

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Crystallography for protein kinase drug design: PKA and SRC case studies

29 September 2017

1 reference

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Protein kinase inhibitors: insights into drug design from structure.

29 September 2017

1 reference

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Purification, crystallization and preliminary X-ray diffraction studies of a complex between G protein-coupled receptor kinase 2 and Gbeta1gamma2.

29 September 2017

1 reference

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Inhibition of protein kinases by balanol: specificity within the serine/threonine protein kinase subfamily

29 September 2017

1 reference

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Molecular design and biological activity of potent and selective protein kinase inhibitors related to balanol

29 September 2017

1 reference

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Nucleoside inhibitors of rhodopsin kinase

29 September 2017

1 reference

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Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase

29 September 2017

1 reference

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Snapshot of activated G proteins at the membrane: the Galphaq-GRK2-Gbetagamma complex.

2 June 2018

1 reference

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Design and crystal structures of protein kinase B-selective inhibitors in complex with protein kinase A and mutants

27 November 2018

1 reference

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Rational design and evaluation of new lead compound structures for selective betaARK1 inhibitors

27 November 2018

1 reference

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Inhibition of the beta-adrenergic receptor kinase by polyanions.

27 November 2018

1 reference

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Peptide inhibitors of G protein-coupled receptor kinases

27 November 2018

1 reference

12 December 2020

Structural analysis of protein kinase A mutants with Rho-kinase inhibitor specificity

1 reference

12 December 2020

Processing of X-ray diffraction data collected in oscillation mode

1 reference

12 December 2020

35 Preparation of antibodies to rhodopsin and the large protein of rod outer segments

1 reference

12 December 2020

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

1 reference

12 December 2020